The Laboratory for Cell Analysis (LCA) is a core facility that provides support to the UCSF ComprehensiveCancer Center. The LCA provides: Flow and image cytometers and the technical support needed to make use of these instruments. Education for UCSF students, staff and faculty in cytometry technology and applications. Expertise for the development of new cytometric assays.Instruments currently available to Cancer Center Members include: a Becton-Dickinson (BD) FACSVantageSE sorter with high-speed cell sorting, three laser excitation, ten detectors, and single-cell cloning; two BDFACSAria Digital cell sorters, three laser excitation, 15 detectors; four BD FACSCalibur flow cytometers withdual lasers capable of four-color analysis, automated sample loading and sorting options; fourZeissConfocal Laser Scanning Microscopes, three with multiphoton lasers, two with spectral emission detectionand live cell scanning capability; two digital video fluorescent microscopes; and two fluorescent microscopeswith high-resolution CCD cameras; a Cellomics ArrayScan HCS automated fluorescence microscopicimaging system for high-content screening and high-content analysis; and a Leica Laser Micro Dissectionmicroscope consisting of an automated upright microscope with a three-dimensional optical control of thedissection laser beam which uses noncontact sample collection by gravity. A variety of computer softwarepackages.and platforms are available to collect and analyze data. In addition, the staff of the LCA offers itsexpertise in the use of this technology as it applies to instrument support and biological applications toCancer Center Members. The LCA Web site is http://cancer.ucsf.edu/lca/index.php.
| Sannino, Sara; Guerriero, Christopher J; Sabnis, Amit J et al. (2018) Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells. J Cell Sci 131: |
| Lam, Christine; Ferguson, Ian D; Mariano, Margarette C et al. (2018) Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica 103:1218-1228 |
| Truillet, Charles; Parker, Matthew F L; Huynh, Loc T et al. (2018) Measuring glucocorticoid receptor expression in vivo with PET. Oncotarget 9:20399-20408 |
| Phillips, Kathryn A; Trosman, Julia R; Deverka, Patricia A et al. (2018) Insurance coverage for genomic tests. Science 360:278-279 |
| Phillips, Kathryn A (2018) Evolving Payer Coverage Policies on Genomic Sequencing Tests: Beginning of the End or End of the Beginning? JAMA 319:2379-2380 |
| Puri, Sapna; Roy, Nilotpal; Russ, Holger A et al. (2018) Replication confers ? cell immaturity. Nat Commun 9:485 |
| An, Zhenyi; Aksoy, Ozlem; Zheng, Tina et al. (2018) Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies. Oncogene 37:1561-1575 |
| Behr, Spencer C; Villanueva-Meyer, Javier E; Li, Yan et al. (2018) Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR. JCI Insight 3: |
| Rubenstein, James L; Geng, Huimin; Fraser, Eleanor J et al. (2018) Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma. Blood Adv 2:1595-1607 |
| An, Zhenyi; Knobbe-Thomsen, Christiane B; Wan, Xiaohua et al. (2018) EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma. Cancer Res 78:6785-6794 |
Showing the most recent 10 out of 192 publications
