The Tissue Procurement Core of the HCCC is designed to procure and make available a wide range of high quality human tissue specimens to investigators from the HCCC while complying with all governing rules and regulations covering such activty. The core was initiated approximately 24 months ago as a collaboration between the HCCC and the Department of Pathology at the University of Iowa Hospitals and Clinics. The Core Director also serves as Director of Anatomic and Surgical Pathology for the Ul Hospitals and Clinics which facilitates this process. Tissue procurement began slowly as processes were developed. To date, the core has collected in excess of 1,000 specimens. At the present time, the core now averages approximately 90 specimens per month. Importantly, both procurement and tissue distribution by the Core are now fully operational. The Tissue Procurement Core is dedicated to the collection, storage, and distribution of high quality human tissue specimens from a variety of disease processes. The process of specimen collection proceeds in a deliberate and step wise fashion. Pre-operative patient consent is mandatory and is obtained either by Tissue Procurement Service Staff or by HCCC/UIHC medical staff at pre-operative visits. Once consent has been obtained, the patient proceeds to surgery to have their appropriate procedure performed. Tissue removed at surgery is then evaluated in the Surgical Pathology Laboratory for suitability of collection by appropriate Department of Pathology staff. Tissue Procurement Core personnel, working in cooperation with Surgical Pathology Laboratory Personnel, take appropriate specimens for archiving. The specimens are snap frozen

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA086862-10
Application #
7900767
Study Section
Subcommittee G - Education (NCI)
Project Start
2009-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
10
Fiscal Year
2009
Total Cost
$104,308
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Schoenfeld, Joshua D; Sibenaller, Zita A; Mapuskar, Kranti A et al. (2018) Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models. Redox Biol 14:417-422
Kelpsch, Daniel J; Tootle, Tina L (2018) Nuclear Actin: From Discovery to Function. Anat Rec (Hoboken) 301:1999-2013
Gupta, Gaurav; Kuppachi, Sarat; Kalil, Roberto S et al. (2018) Treatment for presumed BK polyomavirus nephropathy and risk of urinary tract cancers among kidney transplant recipients in the United States. Am J Transplant 18:245-252
Garje, Rohan; Chau, Justin J; Chung, Jina et al. (2018) Acute Flare of Bullous Pemphigus With Pembrolizumab Used for Treatment of Metastatic Urothelial Cancer. J Immunother 41:42-44
Ruiz Ciancio, Dario; Vargas, Mauricio R; Thiel, William H et al. (2018) Aptamers as Diagnostic Tools in Cancer. Pharmaceuticals (Basel) 11:
Triplette, Matthew; Crothers, Kristina; Mahale, Parag et al. (2018) Risk of lung cancer in lung transplant recipients in the United States. Am J Transplant :
Andrew, Megan; Kim, Yusung; Ginader, Timothy et al. (2018) Reduction of applicator displacement in MR/CT-guided cervical cancer HDR brachytherapy by the use of patient hover transport system. J Contemp Brachytherapy 10:85-90
Buchakjian, Marisa R; Ginader, Timothy; Tasche, Kendall K et al. (2018) Independent Predictors of Prognosis Based on Oral Cavity Squamous Cell Carcinoma Surgical Margins. Otolaryngol Head Neck Surg 159:675-682
Keck, Kendall J; Breheny, Patrick; Braun, Terry A et al. (2018) Changes in gene expression in small bowel neuroendocrine tumors associated with progression to metastases. Surgery 163:232-239
Brandt, Kristin E; Falls, Kelly C; Schoenfeld, Joshua D et al. (2018) Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol 14:82-87

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