The Prevention and Control Program has two broad goals: to develop and conduct research across the cancer continuum that is transdisciplinan/ in nature and translational in focus. Our transdisciplinary research spans from cell to society to address key problems in cancer prevention and control, including disparities, communication, tobacco control, and energy balance. Our translational research evaluates efforts to implement and disseminate evidence-based cancer control into clinical and public health practice, and health policy. To achieve these goals, the Prevention and Control Program: 1. Provides scientific leadership that identifies and actively promotes opportunities for trandisciplinary and translational cancer prevention and control science; 2. Recruits and supports new scientific talent with interests and experience in the two goal areas; 3. Assembles and supports transdisciplinary teams across the Cancer Center; 4. Coordinates seminars, workshops and trainings that help shape the research ideas and skills of cancer prevention and control researchers;and. Builds community partnerships to assure Cancer Center research is responsive to local needs, conducted in real world settings and accountable for timely translation of research into practice. Leading-edge research is underway across the Program;examples include studies examining and reducing breast cancer disparities, integrating communication into cancer care, and exploring ways to improve tobacco control from genetics to social systems. The Prevention and Control Program has 53 members from 11 Departments and 3 Schools (Washington University School of Medicine, Washington University School of Social Work, Saint Louis University). The Program is supported by $24,751,020 in funding of which $11,901,857 is NCI funding and $9,775,280 is other peer reviewed funding. In the last grant period, members of the Program published 480 manuscripts, of which 14.7% represent inter-programmatic and 37.9% resulted from intra-programmatic collaborations.

Public Health Relevance

Cancer continues to pose a major threat to public health. Leading-edge transdisciplinary and translational research is underway across the Prevention and Control Program to reduce this threat by eliminating breast cancer disparities, integrating communication into cancer care, improving tobacco control, energy balance and maximize the benefits of cancer genetics research for cancer prevention.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA091842-13
Application #
8705874
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Stephens, Calvin J; Kashentseva, Elena; Everett, William et al. (2018) Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9. Gene Ther 25:139-156
Trissal, Maria C; Wong, Terrence N; Yao, Juo-Chin et al. (2018) MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis. Cancer Res 78:3510-3521
Copper, Tara Conway; Jeffe, Donna B; Ahmad, Fahd A et al. (2018) Emergency Information Forms for Children With Medical Complexity: A Qualitative Study. Pediatr Emerg Care :
McGill, Bryan E; Barve, Ruteja A; Maloney, Susan E et al. (2018) Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons. J Neurosci 38:200-219
Sharma, Piyush K; Dmitriev, Igor P; Kashentseva, Elena A et al. (2018) Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Ther 25:27-38
Liu, Ying; Colditz, Graham A; Rosner, Bernard A et al. (2018) Comparison of Performance Between a Short Categorized Lifestyle Exposure-based Colon Cancer Risk Prediction Tool and a Model Using Continuous Measures. Cancer Prev Res (Phila) 11:841-848
Dodson, Elizabeth A; Hipp, J Aaron; Lee, Jung Ae et al. (2018) Does Availability of Worksite Supports for Physical Activity Differ by Industry and Occupation? Am J Health Promot 32:517-526
Bauerle, Kevin T; Hutson, Irina; Scheller, Erica L et al. (2018) Glucocorticoid Receptor Signaling Is Not Required for In Vivo Adipogenesis. Endocrinology 159:2050-2061
Garbow, Joel R; Tsien, Christina I; Beeman, Scott C (2018) Preclinical MRI: Studies of the irradiated brain. J Magn Reson 292:73-81
Chiu, Ami; Hartz, Sarah; Smock, Nina et al. (2018) Most Current Smokers Desire Genetic Susceptibility Testing and Genetically-Efficacious Medication. J Neuroimmune Pharmacol 13:430-437

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