Abstract

THIS COMPONENT IS ENTITLED CLINICAL PROTOCOL AND DATA MANAGEMENT PROJECT SUMMARY/ABSTRACT. PROJECT SUMMARY Clinical research is essential to the Siteman Cancer Center?s mission to prevent cancer in the community and transform cancer patient care through scientific discovery. As such, the SCC places the highest priority on its clinical protocol and data management operations within the center?s Clinical Trials Office (CTO). The CTO is designed to support investigators performing clinical research by providing them with access to an effective, efficient and economical clinical research team specializing exclusively in cancer research. This allows for the coordination of robust investigator-initiated trials, industry-sponsored trials and active participation in cooperative groups and consortiums including ALLIANCE, NRG, BMT/CTN, and ET- CTN. Specifically, the CTO is committed to providing exceptional support to SCC members by offering comprehensive services in protocol development, regulatory submission, study coordination, data collection, education, training and financial management.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA091842-16
Application #
9314256
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
16
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Mostafa, Heba H; Thompson, Thornton W; Konen, Adam J et al. (2018) Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation. J Virol 92:
Choi, Jaebok; Cooper, Matthew L; Staser, Karl et al. (2018) Baricitinib-induced blockade of interferon gamma receptor and interleukin-6 receptor for the prevention and treatment of graft-versus-host disease. Leukemia 32:2483-2494
Bartlett, Nancy L; Costello, Brian A; LaPlant, Betsy R et al. (2018) Single-agent ibrutinib in relapsed or refractory follicular lymphoma: a phase 2 consortium trial. Blood 131:182-190
Kalas, Vasilios; Hibbing, Michael E; Maddirala, Amarendar Reddy et al. (2018) Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc Natl Acad Sci U S A 115:E2819-E2828
Yokoyama, Christine C; Baldridge, Megan T; Leung, Daisy W et al. (2018) LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens. J Biol Chem 293:6022-6038
Miller, Jessica; Wang, Steven T; Orukari, Inema et al. (2018) Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes. J Biophotonics 11:e201700232
Song, Wilbur M; Joshita, Satoru; Zhou, Yingyue et al. (2018) Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism. J Exp Med 215:745-760
Gauvain, Karen; Ponisio, Maria Rosana; Barone, Amy et al. (2018) 18F-FDOPA PET/MRI for monitoring early response to bevacizumab in children with recurrent brain tumors. Neurooncol Pract 5:28-36
Cruchaga, Carlos; Del-Aguila, Jorge L; Saef, Benjamin et al. (2018) Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms. Alzheimers Dement 14:205-214
Willet, Spencer G; Lewis, Mark A; Miao, Zhi-Feng et al. (2018) Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis. EMBO J 37:

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