- POPULATION SCIENCES PROGRAM The Population Sciences (PS) Program conducts research on cancer etiology, control, and prevention with the intent of improving public health in the greater bay area and beyond. It makes use of the Greater Bay Area Cancer Registry and other datasets to determine patterns and trends of cancer incidence and mortality within the SCI catchment area, carries out epidemiologic studies to identify additional environmental, genetic, and lifestyle risk factors for cancer, and conducts research in cancer prevention focused on the use of tobacco, physical activity, diet, and obesity as known risk factors. The cross-cutting themes of the program include studies in multiple racial/ethnic groups and studies in high risk populations. The PS Program brings together population-based researchers with basic and clinical scientists and with many external collaborators to carry out its trans-disciplinary research objectives. Co-led by Robert Haile, PhD, Marcia Stefanick, PhD, and Ann Hsing, PhD, the 41 members of the PS Program represent 14 Departments within Stanford University and the Cancer Prevention Institute of California (CPIC). Fifteen members have been newly recruited to the program since the last review and 83% have peer- reviewed funding. The research activities of program members are supported by $7.2M in NCI funding, $13.5M in other NIH support, and $5.6M in other peer-reviewed funding. Since 2009, program members have published 811 manuscripts, of which 13% are inter- and 26% are intra-programmatic; 68% are multi- institutional. The SCI will continue to be invaluable in seeding innovative, highly collaborative projects and assisting with the multi-disciplinary working groups that foster population science projects that have a clear path to translational impact on clinical or public health practices.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA124435-09
Application #
9071756
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2007-06-04
Project End
2021-05-31
Budget Start
2016-07-01
Budget End
2017-05-31
Support Year
9
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
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Champion, Magali; Brennan, Kevin; Croonenborghs, Tom et al. (2018) Module Analysis Captures Pancancer Genetically and Epigenetically Deregulated Cancer Driver Genes for Smoking and Antiviral Response. EBioMedicine 27:156-166
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Im, Hogune; Rao, Varsha; Sridhar, Kunju et al. (2018) Distinct transcriptomic and exomic abnormalities within myelodysplastic syndrome marrow cells. Leuk Lymphoma 59:2952-2962
Huang, Min; Zhu, Li; Garcia, Jacqueline S et al. (2018) Brd4 regulates the expression of essential autophagy genes and Keap1 in AML cells. Oncotarget 9:11665-11676
Chiou, Shin-Heng; Dorsch, Madeleine; Kusch, Eva et al. (2018) Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. Sci Rep 8:14008
Breslow, David K; Hoogendoorn, Sascha; Kopp, Adam R et al. (2018) A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nat Genet 50:460-471

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