Abstract

The Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC) requests $175,000 in developmental funds, 17.5% of the overall direct Cancer Center Support Grant (CCSG) request, that will be used specifically to: Provide three to five pilot research funding grants to HCC members, a total of $120,000 per year, to promote translational research in high priority areas as articulated by the HCC Senior Leadership ? Recruit one new faculty scientist with an emphasis on translational immunotherapy in Years 1-3 ($55,000 each year) and a second recruit, a drug discovery scientist, in Years 4-5 ($55,000 each year)

Public Health Relevance

The Hollings Cancer Center requests Developmental Funds from the Cancer Center Support Grant to fund pilot research projects and to recruit new faculty to MUSC;both endeavors will support the important goal of translational or

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA138313-04
Application #
8377238
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
4
Fiscal Year
2012
Total Cost
$244,314
Indirect Cost
$78,678

  Institution

Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Zhong, Zhi; Lemasters, John J (2018) A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease. Alcohol Clin Exp Res 42:2072-2089
Sizemore, Gina M; Balakrishnan, Subhasree; Thies, Katie A et al. (2018) Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun 9:2783
Hathaway-Schrader, Jessica D; Doonan, Bently P; Hossain, Azim et al. (2018) Autophagy-dependent crosstalk between GILT and PAX-3 influences radiation sensitivity of human melanoma cells. J Cell Biochem 119:2212-2221
Parikh, Rasesh Y; Lin, Haifan; Gangaraju, Vamsi K (2018) A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis in Drosophila. J Biol Chem 293:9140-9147
Daenthanasanmak, Anusara; Wu, Yongxia; Iamsawat, Supinya et al. (2018) PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity. J Clin Invest 128:2787-2801
Rosenzweig, Steven A (2018) Acquired Resistance to Drugs Targeting Tyrosine Kinases. Adv Cancer Res 138:71-98
Min, Kyung-Won; Zealy, Richard W; Davila, Sylvia et al. (2018) Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. Aging Cell 17:e12753
Alawieh, Ali; Langley, E Farris; Weber, Shannon et al. (2018) Identifying the role of complement in triggering neuroinflammation after traumatic brain injury. J Neurosci :
Metelli, Alessandra; Salem, Mohammad; Wallace, Caroline H et al. (2018) Immunoregulatory functions and the therapeutic implications of GARP-TGF-? in inflammation and cancer. J Hematol Oncol 11:24
Helke, Kristi; Angel, Peggi; Lu, Ping et al. (2018) Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis. Sci Rep 8:1627

Showing the most recent 10 out of 536 publications