Abstract

The Protocol Review and Monitoring System (PRMS) of the Tisch Cancer Institute (TCI) oversees all cancer related clinical research conducted at the Mount Sinai Health System (MSHS). The major goal of the PRMS is to assure adequate internal oversight of the scientific aspects of cancer-related research by providing a rigorous initial scientific review and performing ongoing monitoring for scientific progress and accrual onto active cancer protocols. Protocol review is comprised of three components: Biostatistics Design Workshop, Disease Focus Groups, and the Protocol Review and Monitoring Committee (PRMC). Only the PRMC has the authority to open protocols that meet the scientific merit and priorities of the TCI and to terminate protocols that do not demonstrate scientific progress.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA196521-06
Application #
10022670
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
2015-08-01
Project End
2025-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Zhang, Maomao; Di Martino, Julie S; Bowman, Robert L et al. (2018) Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins. Cancer Discov 8:1006-1025
Yip, Rowena; Li, Kunwei; Liu, Li et al. (2018) Controversies on lung cancers manifesting as part-solid nodules. Eur Radiol 28:747-759
Leiter, Amanda; Bickell, Nina A; LeRoith, Derek et al. (2018) Statin Use and Breast Cancer Prognosis in Black and White Women. Horm Cancer 9:55-61
Fujiwara, Naoto; Nakagawa, Hayato; Enooku, Kenichiro et al. (2018) CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity. Gut 67:1493-1504
Hogstad, Brandon; Berres, Marie-Luise; Chakraborty, Rikhia et al. (2018) RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. J Exp Med 215:319-336
Wu, Lisa M; Amidi, Ali; Tanenbaum, Molly L et al. (2018) Computerized cognitive training in prostate cancer patients on androgen deprivation therapy: a pilot study. Support Care Cancer 26:1917-1926
Chang, Sanders; Ru, Meng; Moshier, Erin L et al. (2018) The impact of radiation treatment planning technique on unplanned hospital admissions. Adv Radiat Oncol 3:647-654
Formenti, Silvia C; Rudqvist, Nils-Petter; Golden, Encouse et al. (2018) Radiotherapy induces responses of lung cancer to CTLA-4 blockade. Nat Med 24:1845-1851
Likhterov, Ilya; Ru, Meng; Ganz, Cindy et al. (2018) Objective and subjective hyposalivation after treatment for head and neck cancer: Long-term outcomes. Laryngoscope 128:2732-2739
Strub, Thomas; Ghiraldini, Flavia G; Carcamo, Saul et al. (2018) SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling. Nat Commun 9:3440

Showing the most recent 10 out of 143 publications