The University of Washington NIDA P30 Center uses cutting-edge genomic and proteomic technologiescombined with computational approaches to study HCV, HIV-1, HCV-associated liver disease, andHCV/HIV-1 co-infection public health problems that are direct consequences of drug abuse and addiction.Dual infection is a growing public concern, and little is known of how the interactions between these virusesand they impact disease progression and treatment. The Center has a strong multidisciplinary character,exemplified by diverse technologies, the participation of investigators from basic science and clinicalmedicine, and the use of a variety of biologic resources and experimental models. We have learned thoughexperience that a strong administrative and organizational structure is vital to the Center's ability tosuccessfully carry out multidisciplinary research and to promote synergy between programmatic elements.The Administrative Core has become of even greater importance as the Center has established itself as anational resource and has taken on an increasing number of collaborations with outside investigators. In thisCore, we outline in detail our administrative structure, the role of the Director, Administrator, and AdvisoryBoards in managing Center activities, and methods for project planning, priority setting, and evaluation. Wealso describe procedures for establishing and managing new external collaborations. Clearly, the success olthe Administrative Core is dependent upon its personnel, and we have assembled an experienced team ofDirectors and Administrators. We are also fortunate to have Internal and External Advisory Boards that arecomposed of highly regarded experts in the fields of HCV, liver biology, virology/immunology, drug addiction,proteomics, and bioinformatics.
The Specific Aims of the Administrative Core are to: 1) Provide anorganizational and programmatic structure to promote scientific interactions, publications, and future grantapplications. 2) Provide oversight, planning, priority setting, and decision-making processes. 3) Ensure thathe Center meets all criteria for a NIDA P30 Core Support Center. The Administrative Core is tasked withensuring that the Center continues to meet all criteria described in the NIDA Research Center GranConsolidated Program and Review Guidelines, including a data sharing plan, state-of-the-art facilities,innovation, multidisciplinary involvement, thematic integration, and synergy among Center components.
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