Abstract

The long term goals for the Protein and Lipid Separation and Profiling Core are to leverage existing Keck protein differential profiling platforms and develop new technologies to better understand and characterize the mechanisms that underlie substance abuse.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
5P30DA018343-05
Application #
7638442
Study Section
Special Emphasis Panel (ZDA1)
Project Start
2008-06-01
Project End
2009-05-31
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
5
Fiscal Year
2008
Total Cost
$525,693
Indirect Cost

  Institution

Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Li, Daniel; Musante, Veronica; Zhou, Wenliang et al. (2018) Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. J Biol Chem 293:11179-11194
Levy, Aaron D; Xiao, Xiao; Shaw, Juliana E et al. (2018) Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function. Cell Rep 24:1523-1535
Mervosh, Nicholas L; Wilson, Rashaun; Rauniyar, Navin et al. (2018) Granulocyte-Colony-Stimulating Factor Alters the Proteomic Landscape of the Ventral Tegmental Area. Proteomes 6:
Kumar, Nikit; Leonzino, Marianna; Hancock-Cerutti, William et al. (2018) VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J Cell Biol 217:3625-3639
Milovanovic, Dragomir; Wu, Yumei; Bian, Xin et al. (2018) A liquid phase of synapsin and lipid vesicles. Science 361:604-607
Benedetti, Lorena; Barentine, Andrew E S; Messa, Mirko et al. (2018) Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci U S A 115:E2238-E2245
Rao, Vishwanatha K; Zavala, Gerardo; Deb Roy, Abhijit et al. (2018) A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells. J Cell Physiol :
Bian, Xin; Saheki, Yasunori; De Camilli, Pietro (2018) Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport. EMBO J 37:219-234
Wilson, Rashaun S; Nairn, Angus C (2018) Making brain proteomics true to type. Nat Biotechnol 36:149-150
Carlyle, Becky C; Kitchen, Robert R; Kanyo, Jean E et al. (2017) A multiregional proteomic survey of the postnatal human brain. Nat Neurosci 20:1787-1795

Showing the most recent 10 out of 185 publications