Under the direction of Rick Hoyle, the primary objectives of the Methodology and Statistics Core in the Duke Transdisciplinary Prevention Research Center (TPRC) are to facilitate, encourage, strengthen, and expand the quality of collection, management, and analysis of data in research on the prevention of adolescent substance abuse. The Core will provide resources and expertise that contribute to the development, execution, analysis, and publication of high quality prevention science focused on adolescent substance abuse. The Core will ensure professional quality consultation and collaborative opportunities as specified in the following aims. 1. Provide leadership in the application of rigorous and innovative statistical methods in TPRC research. 2. Provide data-warehousing functions that include data management;storage and retrieval of electronic data;and quality control and assurance of electronic data. 3. Expand advanced data-analytic services offered by the Core to meeting the varied and emerging needs of TPRC investigators. 4. Promote methodological and statistical education and training opportunities for TPRC investigators and the broader community of prevention scientists at Duke and UNC.
These aims will be pursued by a multidisciplinary team of experts who are experienced providers of methodological and statistical support for complex, large-scale, funded research projects. The Methodology and Statistics Core will provide a crucial link between the network of prevention scientists at Duke and the methodologists and statisticians distributed across units at the institution. In addition, the Methodology and Statistics Core will offer leadership to the broader substance abuse prevention research effort by providing training and technology transfer in the application of state-of-the-art statistical methods, providing a readily accessible structure for interdisciplinary sharing of ideas, and training graduate students and postdoctoral fellows in prevention science methods. The Methodology and Statistics Core of the Duke Transdisciplinary Prevention Research Center will reduce the public health burden of adolescent substance use by enhancing the capacity of investigators to analyze their data in ways that facilitate novel prevention programs and activities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
5P30DA023026-02
Application #
7899958
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
2
Fiscal Year
2009
Total Cost
$577,912
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Odgers, Candice (2018) Smartphones are bad for some teens, not all. Nature 554:432-434
Anderson, Sarah L; Zheng, Yao; McMahon, Robert J (2018) Do Callous-Unemotional Traits and Conduct Disorder Symptoms Predict the Onset and Development of Adolescent Substance Use? Child Psychiatry Hum Dev 49:688-698
Hanson, Jamie L; Knodt, Annchen R; Brigidi, Bartholomew D et al. (2018) Heightened connectivity between the ventral striatum and medial prefrontal cortex as a biomarker for stress-related psychopathology: understanding interactive effects of early and more recent stress. Psychol Med 48:1835-1843
King, Kevin M; Luk, Jeremy W; Witkiewitz, Katie et al. (2018) Externalizing Behavior Across Childhood as Reported by Parents and Teachers: A Partial Measurement Invariance Model. Assessment 25:744-758
Zheng, Yao; Albert, Dustin; McMahon, Robert J et al. (2018) Glucocorticoid Receptor (NR3C1) Gene Polymorphism Moderate Intervention Effects on the Developmental Trajectory of African-American Adolescent Alcohol Abuse. Prev Sci 19:79-89
Dotterer, Hailey L; Hyde, Luke W; Swartz, Johnna R et al. (2017) Amygdala reactivity predicts adolescent antisocial behavior but not callous-unemotional traits. Dev Cogn Neurosci 24:84-92
Fleming, Andrew P; McMahon, Robert J; King, Kevin M (2017) Structured Parent-Child Observations Predict Development of Conduct Problems: the Importance of Parental Negative Attention in Child-Directed Play. Prev Sci 18:257-267
Okado, Yuko; Ewing, Emily; Rowley, Christina et al. (2017) Trajectories of Mental Health-Related Service Use Among Adolescents With Histories of Early Externalizing Problems. J Adolesc Health 61:198-204
Swartz, Johnna R; Hariri, Ahmad R; Williamson, Douglas E (2017) An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents. Mol Psychiatry 22:209-214
Copeland, William E; Hill, Sherika; Costello, E Jane et al. (2017) Cannabis Use and Disorder From Childhood to Adulthood in a Longitudinal Community Sample With American Indians. J Am Acad Child Adolesc Psychiatry 56:124-132.e2

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