Administrative Plan (Administration Core)Note: This section is provided to give reviewers information relating the adequacy of the administrativeplan as it refers to Core A. With the exception of some updating, the text is essentially the same as inthe competitive renewal submitted October 1st, 2004. The Administration Core was funded in thecompetitive renewal, and is not being reviewed in this supplemental application.2.1 Administrative Structure. The administrative structure is modest (-14% of the total direct costs for theentire RMTSC), and focuses on maximizing interaction among members of the RMTSC and in facilitatingefficient provision of services by the research Cores. There are frequent daily interactions between allmembers of the RMTSC. The Co-Director of the Center and Principal Investigator is Dr. Diego Restrepo. Hisresponsibility is the overall oversight of the facility and coordination of Core personnel. Dr. Restrepo hasconsiderable administrative experience as Co-Director of the RMTSC and Director of the NeuroscienceProgram at UCDHSC. Dr. Thomas Finger, who has extensive administrative experience as past Director of theRMTSC Program Project (P01), serves as Co-Director. He advises Dr. Restrepo in running of the RMTSC andwill oversee running of the Center in Dr. Restrepo's absence. The two Co-Directors have interacted well duringthe present period of support. Dr. Robin Michaels, who has considerable administrative experience, performsday-to-day administrative procedures. She also has a solid background in research and as a result ofteninteracts with members of the laboratories at a scientific level (see vitae). An Administrative Committeeconsisting of all P.l.s of RMTSC qualifying research base grants, chaired by Dr. Restrepo meets semi-annually,or as often as necessary to specifically discuss administrative procedures. The members of the RMTSC arehighly interactive, and this administrative structure has proved to be flexible, yet solid during the present periodof support.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
5P30DC004657-09
Application #
7692400
Study Section
Special Emphasis Panel (ZDC1-SRB-W (46))
Project Start
2008-09-01
Project End
2010-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
9
Fiscal Year
2008
Total Cost
$75,968
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Romanov, Roman A; Lasher, Robert S; High, Brigit et al. (2018) Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex. Sci Signal 11:
Stratford, J M; Larson, E D; Yang, R et al. (2017) 5-HT3A -driven green fluorescent protein delineates gustatory fibers innervating sour-responsive taste cells: A labeled line for sour taste? J Comp Neurol 525:2358-2375
Li, Anan; Guthman, Ethan M; Doucette, Wilder T et al. (2017) Behavioral Status Influences the Dependence of Odorant-Induced Change in Firing on Prestimulus Firing Rate. J Neurosci 37:1835-1852
Castillo-Azofeifa, David; Losacco, Justin T; Salcedo, Ernesto et al. (2017) Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance. Development 144:3054-3065
Chang, Weipang; Kanda, Hirosato; Ikeda, Ryo et al. (2017) Serotonergic transmission at Merkel discs: modulation by exogenously applied chemical messengers and involvement of Ih currents. J Neurochem 141:565-576
Finger, Thomas E; Bartel, Dianna L; Shultz, Nicole et al. (2017) 5HTR3A-driven GFP labels immature olfactory sensory neurons. J Comp Neurol 525:1743-1755
Gaillard, Dany; Bowles, Spencer G; Salcedo, Ernesto et al. (2017) ?-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. PLoS Genet 13:e1006990
Stratford, Jennifer M; Thompson, John A; Finger, Thomas E (2017) Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice. J Comp Neurol 525:271-290
Chang, Weipang; Kanda, Hirosato; Ikeda, Ryo et al. (2016) Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals. Proc Natl Acad Sci U S A 113:E5491-500
von Holstein-Rathlou, Stephanie; BonDurant, Lucas D; Peltekian, Lila et al. (2016) FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver. Cell Metab 23:335-43

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