The Scientific Synergy Core (Core A) is the intellectual fulcrum of this research core center. It represents alow-cost high impact core which will dramatically strengthen auditory and vestibular sciences at theUniversity of Michigan and in the research community in the Michigan - Ohio region. Specifically, the corewill promote scientific information exchange and scholarly discussions through regular contacts, furthertechnology transfer to enhance research, aid principal investigators in the training of students, fellows andstaff, and encourage new and increased collaboration through the formation of special interest groups.Within the P30 research cores the regular contacts between the principal investigators and key personnel ofthe cores will remain the customary avenue of communication. Going beyond these interactions, however, allstudents, fellows, and laboratory staff are included in the meetings of the interest groups of Core A and thethree annual meetings that we are proposing. Despite its ambitions of creating a multi-institutional synergycore, Core A does not add significantly to the P30 budget because of the proximity of all participatinglaboratories, which eliminates the necessity for any overnight stays and associated costs for meetings,discussions, or service training.While the rules of the P30 restricts its use to programs with appropriate grant support, we feel that theintellectual environment created by Core A must not be limited to those with currently funded grants. Core Awill serve the spirit of the P30 and the mission of the NIDCD by including young investigators trying toestablish themselves and research groups between funding. In fact, we argue that the inclusion of thesescientists may become one of the most important aspects of this core in strengthening and promotingNIDCD-mission research. The intellectual interactions will build mentoring relationships, encouragecollaborations, and through discussion, enhance the quality of of our research, our grant applications and ourpublications.
These aims will aid the growth of young groups and make established ones more competitive intheir attempts to obtain grant funding.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
2P30DC005188-06
Application #
7317628
Study Section
Special Emphasis Panel (ZDC1-SRB-O (12))
Project Start
2007-07-01
Project End
2012-06-30
Budget Start
2007-07-01
Budget End
2008-07-31
Support Year
6
Fiscal Year
2007
Total Cost
$13,274
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Heeringa, Amarins N; Wu, Calvin; Shore, Susan E (2018) Multisensory Integration Enhances Temporal Coding in Ventral Cochlear Nucleus Bushy Cells. J Neurosci 38:2832-2843
Schvartz-Leyzac, Kara C; Pfingst, Bryan E (2018) Assessing the Relationship Between the Electrically Evoked Compound Action Potential and Speech Recognition Abilities in Bilateral Cochlear Implant Recipients. Ear Hear 39:344-358
Altschuler, Richard A; Halsey, Karin; Kanicki, Ariane et al. (2018) Small Arms Fire-like noise: Effects on Hearing Loss, Gap Detection and the Influence of Preventive Treatment. Neuroscience :
Devare, Jenna; Gubbels, Samuel; Raphael, Yehoash (2018) Outlook and future of inner ear therapy. Hear Res 368:127-135
Avenarius, Matthew R; Jung, Jae-Yun; Askew, Charles et al. (2018) Grxcr2 is required for stereocilia morphogenesis in the cochlea. PLoS One 13:e0201713
Carlson, Krystin; Schacht, Jochen; Neitzel, Richard L (2018) Assessing ototoxicity due to chronic lead and cadmium intake with and without noise exposure in the mature mouse. J Toxicol Environ Health A 81:1041-1057
Schaefer, Stacy A; Higashi, Atsuko Y; Loomis, Benjamin et al. (2018) From Otic Induction to Hair Cell Production: Pax2EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model. Stem Cells Dev 27:237-251
Heeringa, Amarins N; Wu, Calvin; Chung, Christopher et al. (2018) Glutamatergic Projections to the Cochlear Nucleus are Redistributed in Tinnitus. Neuroscience 391:91-103
Altschuler, R A; Kanicki, A; Martin, C et al. (2018) Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea. Hear Res 370:11-15
Yao, Hui; Hill, Sophie F; Skidmore, Jennifer M et al. (2018) CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development. JCI Insight 3:

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