Administrative Structure The scientific aspects of the Core Center, specifically the promotion of information exchange, scientific interactions, and the fostering of collaborations will be coordinated by the newly created Scientific Synergy Core (Core A). The charge to the administrative core therefore is purely organizational to 1. integrate and supervise the research core activities; 2. facilitate the operation of the cores by resolving issues of space and facilities; 3. assume administrative tasks for all cores such as personnel management and financial operations; 4. carry out or facilitate contacts with University of Michigan administration and granting agencies; 5. coordinate the submission of progress reports and renewal grant applications. Dr. Jochen Schacht is the Director of the proposed University of Michigan Hearing Research Core Center and will be responsible for both the overall goals and the administration of this grant. The research and user base comprises investigators from four institutions: The University of Michigan, Michigan State University, Wayne State University, and University of Toledo;however, all core facilities and activities will be located at the University of Michigan. Dr. Schacht has been on the faculty of the Kresge Hearing Research Institute since 1972 and holds the position of Professor of Biological Chemistry in Otolaryngology and Director of the Kresge Hearing Research Institute. He is PI on the current P30 and has extensive experience in the coordination of similar multi-investigator projects. He was the PI on a NIDCD-funded training grant """"""""Sensory Mechanisms and Disorders"""""""" from 1983 to 1996 (continued by Dr. Pfingst), on a NIDCD-supported Program Project grant """"""""Perception and Processing of Complex Signals"""""""" from 1991 to 1996 (continued by Dr. Middlebrooks) and on a NIDCD-sponsored Program Project grant """"""""Molecular Mechanisms of Cochlear Function and Dysfunction"""""""" from 1996 to December 2001 when P01s were discontinued by NIDCD. Currently, Dr. Schacht is PI on an interdepartmental Program Project Grant on age-related hearing loss funded by NIA. Dr. Schacht will be supported in all aspects of research core organization by the directors of the individual research service cores, Drs. Altschuler, Dolan, Middlebrooks, and Raphael. Each research core has its own structure designed to meet the needs of the investigators and to maximize its efficiency. While the Research Core directors report to Dr. Schacht on core activities and progress, they determine the day-to-day operations of their cores as spelled out in the description of the Research Cores. In the administrative aspects of the program, Dr. Schacht is assisted by a team consisting of Ms. Jackie Blake, an experienced administrator, Mr. Gary Dootz, Administrative Assistant and grants manager, and Ms. Sue Ann Kelch, Finance Coordinator. The team will oversee all administrative services provided for the cores including fiscal planning and management, financial oversight and analysis, compilation of progress reports to NIH, personnel services, facilities and equipment needs, and resource allocations. Ms. Blake will primarily be responsible for the paperwork and recordkeeping for Core Center personnel and payroll and act as the liaison between the co-investigators of this Center and The University of Michigan's central services (The Medical School, Personnel, Plant and Maintenance Departments). Mr. Dootz is responsible for contacts with the Division of Research Development and Administration as well as with NIH. The part-time Finance Coordinator will provide the direct financial services required for the Center, including financial recordkeeping, monthly reconciliation of statements of accounts, and assistance with budget planning and review. Dr. Schacht will receive formal monthly reports on the current and planned expenses of each core and review these reports with the Research Core Directors.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
5P30DC005188-10
Application #
8299402
Study Section
Special Emphasis Panel (ZDC1)
Project Start
Project End
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
10
Fiscal Year
2011
Total Cost
$104,371
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Heeringa, Amarins N; Wu, Calvin; Shore, Susan E (2018) Multisensory Integration Enhances Temporal Coding in Ventral Cochlear Nucleus Bushy Cells. J Neurosci 38:2832-2843
Schvartz-Leyzac, Kara C; Pfingst, Bryan E (2018) Assessing the Relationship Between the Electrically Evoked Compound Action Potential and Speech Recognition Abilities in Bilateral Cochlear Implant Recipients. Ear Hear 39:344-358
Altschuler, Richard A; Halsey, Karin; Kanicki, Ariane et al. (2018) Small Arms Fire-like noise: Effects on Hearing Loss, Gap Detection and the Influence of Preventive Treatment. Neuroscience :
Devare, Jenna; Gubbels, Samuel; Raphael, Yehoash (2018) Outlook and future of inner ear therapy. Hear Res 368:127-135
Avenarius, Matthew R; Jung, Jae-Yun; Askew, Charles et al. (2018) Grxcr2 is required for stereocilia morphogenesis in the cochlea. PLoS One 13:e0201713
Carlson, Krystin; Schacht, Jochen; Neitzel, Richard L (2018) Assessing ototoxicity due to chronic lead and cadmium intake with and without noise exposure in the mature mouse. J Toxicol Environ Health A 81:1041-1057
Schaefer, Stacy A; Higashi, Atsuko Y; Loomis, Benjamin et al. (2018) From Otic Induction to Hair Cell Production: Pax2EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model. Stem Cells Dev 27:237-251
Heeringa, Amarins N; Wu, Calvin; Chung, Christopher et al. (2018) Glutamatergic Projections to the Cochlear Nucleus are Redistributed in Tinnitus. Neuroscience 391:91-103
Altschuler, R A; Kanicki, A; Martin, C et al. (2018) Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea. Hear Res 370:11-15
Yao, Hui; Hill, Sophie F; Skidmore, Jennifer M et al. (2018) CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development. JCI Insight 3:

Showing the most recent 10 out of 287 publications