The overall objective of the oral health Research Clinical Core Center at The University of Iowa is to provide an optimum physical and intellectual environment in which investigations pertaining to human subjects can be conducted with maximum regard for their welfare. The Center will facilitate the transfer of knowledge from the laboratory to patient populations, thus improving prevention, diagnosis and treatment of oral disease. It will also provide opportunities for training of junior investigators, for the application of new technology and for the development of interdisciplinary programs within the University. The Center will consist of four cores; the Administrative Core, the Biostatistics, Education and Dissemination Core, the Clinical Resources Core, an the Laboratory Resources Core. Each will have a director responsible to the Center Director. There will be a Steering Committee to assist the Director and an External Review Panel. The Biostatistics, Education and Dissemination Core will be a critical component of the Center providing not only advice and assistance with experimental design and data analysis but also training. Clinically-relevant research will be disseminated via modern electronic technology. The Clinical Resources Core provides the facilities and staff to conduct clinical research. There will be access to a wide range of human subjects including several established special populations. The Laboratory Resources Core will be sufficiently flexible to meet present and future research needs; it will be able to support projects in Biomaterials, Cardiology, Microbiology and immunology, and Oral Soft Tissues. Research projects to be carried out in the cores will include those associated with existing funded grants as well as pilot studies that will lead to submission of larger projects for funding. The Center will complement the existing research resources of the Dentistry and provide an important facility for the College and the University. Nationally, the combination of an existing facility involved in clinical research, the availability of basic and laboratory support, the existence of normal and special populations and the use of the biostatistical expertise on campus represent a unique set of physical and human resources. Knowledge gained will improve patient care in the clinics and in the community.
| Bhagavatula, Pradeep; Levy, Steven M; Broffitt, Barbara et al. (2016) Timing of fluoride intake and dental fluorosis on late-erupting permanent teeth. Community Dent Oral Epidemiol 44:32-45 |
| Watkins, Catherine; Ettinger, Ronald L; Cowen, Howard et al. (2012) Iowa dentists' involvement in care for patients who are homebound. Spec Care Dentist 32:251-8 |
| Cannon, Hyrum M; Broffitt, Barbara; Levy, Steven M et al. (2010) Longitudinal changes in parental satisfaction: mixed dentition esthetics. J Dent Child (Chic) 77:166-73 |
| Hong, Liang; Levy, Steven M; Broffitt, Barbara et al. (2006) Timing of fluoride intake in relation to development of fluorosis on maxillary central incisors. Community Dent Oral Epidemiol 34:299-309 |
| Hong, Liang; Levy, Steven M; Warren, John J et al. (2006) Fluoride intake levels in relation to fluorosis development in permanent maxillary central incisors and first molars. Caries Res 40:494-500 |
| Cho, Peter; Schneider, Galen B; Kellogg, Bradley et al. (2006) Effect of glucocorticoid-induced osteoporotic-like conditions on osteoblast cell attachment to implant surface microtopographies. Implant Dent 15:377-85 |
| Levy, Steven M; Hong, Liang; Warren, John J et al. (2006) Use of the fluorosis risk index in a cohort study: the Iowa fluoride study. J Public Health Dent 66:92-6 |
| Hong, Liang; Watkins, Catherine A; Ettinger, Ronald L et al. (2005) Effect of topical fluoride and fluoride varnish on in vitro root surface lesions. Am J Dent 18:182-7 |
| Hong, Liang; Levy, Steven M; Warren, John J et al. (2005) Association of amoxicillin use during early childhood with developmental tooth enamel defects. Arch Pediatr Adolesc Med 159:943-8 |
| Slayton, R L; Cooper, M E; Marazita, M L (2005) Tuftelin, mutans streptococci, and dental caries susceptibility. J Dent Res 84:711-4 |
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