Abstract

The Diabetes Center has been organized around seven core units--Administration Core, Biostatistics Core, Physiology Core, Radioimmunoassay Core, Clinical Research Core, Cytohistochemistry Core, and Tissue Culture Core. These are planned to support research studies by 59 affiliated investigators. They are designed to: (1) provide for better access to patients with diabetes and suitable controls and to complex animal models such as primates for diabetes-related investigation; (2) support the development, access, and efficient use of technologies relevant to diabetes; (3) coordinate, stimulate, and support collaborative studies between investigators interested in diabetes at the University of Washington; (4) provide initial support for new investigators in the field of diabetes and to stimulate the application of knowledge in related fields to study of problems in diabetes. A pilot and feasibility program of five requests for new studies in the field of diabetes is included with the application.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK017047-12
Application #
3101930
Study Section
(SRC)
Project Start
1977-06-01
Project End
1989-03-31
Budget Start
1986-06-01
Budget End
1989-03-31
Support Year
12
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Wall, Valerie Z; Barnhart, Shelley; Kanter, Jenny E et al. (2018) Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome. JCI Insight 3:
Toledo, Frederico G S; Johannsen, Darcy L; Covington, Jeffrey D et al. (2018) Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals. Diabetologia 61:466-475
Ferreccio, Amy; Mathieu, Julie; Detraux, Damien et al. (2018) Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Cell Cycle 17:535-549
Mukamal, Kenneth J; Siscovick, David S; de Boer, Ian H et al. (2018) Metabolic Clusters and Outcomes in Older Adults: The Cardiovascular Health Study. J Am Geriatr Soc 66:289-296
Tang, Jingjing; Frey, Jeremy M; Wilson, Carole L et al. (2018) Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation. Mol Cell Biol :
Lynch, Kristian F; Lee, Hye-Seung; Törn, Carina et al. (2018) Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident ?-cell autoantibodies. J Autoimmun 86:93-103
Parilla, Jacqueline H; Willard, Joshua R; Barrow, Breanne M et al. (2018) A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes. J Diabetes Res 2018:6106051
Bornfeldt, Karin E; Kramer, Farah; Batorsky, Anna et al. (2018) A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis. Am J Pathol 188:343-352
Wang, Ke; Zelnick, Leila R; Hoofnagle, Andrew N et al. (2018) Alteration of HDL Protein Composition with Hemodialysis Initiation. Clin J Am Soc Nephrol 13:1225-1233
Bharmal, Nazleen H; McCarthy, William J; Gadgil, Meghana D et al. (2018) The Association of Religious Affiliation with Overweight/Obesity Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. J Relig Health 57:33-46

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