Abstract

The Diabetes Center has been organized around seven core units--Administration Core, Biostatistics Core, Physiology Core, Radioimmunoassay Core, Clinical Research Core, Cytohistochemistry Core, and Tissue Culture Core. These are planned to support research studies by 59 affiliated investigators. They are designed to: (1) provide for better access to patients with diabetes and suitable controls and to complex animal models such as primates for diabetes-related investigation; (2) support the development, access, and efficient use of technologies relevant to diabetes; (3) coordinate, stimulate, and support collaborative studies between investigators interested in diabetes at the University of Washington; (4) provide initial support for new investigators in the field of diabetes and to stimulate the application of knowledge in related fields to study of problems in diabetes. A pilot and feasibility program of five requests for new studies in the field of diabetes is included with the application.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
3P30DK017047-12S2
Application #
3101929
Study Section
(SRC)
Project Start
1977-06-01
Project End
1989-03-31
Budget Start
1988-06-01
Budget End
1989-03-31
Support Year
12
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Wacker, Bradley K; Dronadula, Nagadhara; Bi, Lianxiang et al. (2018) Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol 38:206-217
Wander, Pandora L; Hayashi, Tomoshige; Sato, Kyoko Kogawa et al. (2018) Design and validation of a novel estimator of visceral adipose tissue area and comparison to existing adiposity surrogates. J Diabetes Complications 32:1062-1067
Han, Seung Jin; Fujimoto, Wilfred Y; Kahn, Steven E et al. (2018) Change in visceral adiposity is an independent predictor of future arterial pulse pressure. J Hypertens 36:299-305
Xiang, Anny H; Trigo, Enrique; Martinez, Mayra et al. (2018) Impact of Gastric Banding Versus Metformin on ?-Cell Function in Adults With Impaired Glucose Tolerance or Mild Type 2 Diabetes. Diabetes Care 41:2544-2551
Coleman, Brantley; Topalidou, Irini; Ailion, Michael (2018) Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans. Genetics 209:523-535
Lemaitre, Rozenn N; Yu, Chaoyu; Hoofnagle, Andrew et al. (2018) Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study. Diabetes 67:1663-1672
Hwang, You Cheol; Fujimoto, Wilfred Y; Kahn, Steven E et al. (2018) Predictors of Incident Type 2 Diabetes Mellitus in Japanese Americans with Normal Fasting Glucose Level. Diabetes Metab J 42:198-206
Rubinow, Katya B; Vaisar, Tomas; Chao, Jing H et al. (2018) Sex steroids mediate discrete effects on HDL cholesterol efflux capacity and particle concentration in healthy men. J Clin Lipidol 12:1072-1082
Nagy, Nadine; de la Zerda, Adi; Kaber, Gernot et al. (2018) Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. J Biol Chem 293:567-578
Greenbaum, Carla J; Speake, Cate; Krischer, Jeffrey et al. (2018) Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Diabetes 67:1216-1225

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