The Clinical Research Core provides Affiliate Investigators with access to human volunteers, both diabetic and controls, for clinical research. Services include recruitment of volunteers for studies and obtaining blood or other specimens from research subjects and delivering these specimens to the appropriate laboratories. The Clinical Research Core has been crucial in supporting both investigations which require only a few subjects (or specimens) as well as those which require very large numbers of subjects. In addition to the Director and Associate Director, the Clinical Research Core staff includes one full time Research Study Coordinator and half-time Administrative Coordinator. Variable costs incurred by the Clinical Research Core are reimbursed as program income to the Core as part of a charge-back system to Affiliate Investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK017047-30
Application #
7550723
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
30
Fiscal Year
2006
Total Cost
$125,972
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hannon, Tamara S; Kahn, Steven E; Utzschneider, Kristina M et al. (2018) Review of methods for measuring ?-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium. Diabetes Obes Metab 20:14-24
Banks, William A; Kovac, Andrej; Morofuji, Yoichi (2018) Neurovascular unit crosstalk: Pericytes and astrocytes modify cytokine secretion patterns of brain endothelial cells. J Cereb Blood Flow Metab 38:1104-1118
de Groot, Mary; Marrero, David; Mele, Lisa et al. (2018) Depressive Symptoms, Antidepressant Medication Use, and Inflammatory Markers in the Diabetes Prevention Program. Psychosom Med 80:167-173
Roshandel, Delnaz; Gubitosi-Klug, Rose; Bull, Shelley B et al. (2018) Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes. Diabetologia 61:1098-1111
Guillory, Bobby; Jawanmardi, Nicole; Iakova, Polina et al. (2018) Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBP?-p300/DGAT1 pathway. Aging Cell 17:
Brinkley, Tina E; Anderson, Andrea; Soliman, Elsayed Z et al. (2018) Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial. Am J Hypertens 31:541-548
Kanter, Jenny E; Kramer, Farah; Barnhart, Shelley et al. (2018) A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome. Diabetes 67:946-959
Redondo, Maria J; Geyer, Susan; Steck, Andrea K et al. (2018) TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes. Diabetes Care 41:311-317
Kramer, Philip A; Duan, Jicheng; Gaffrey, Matthew J et al. (2018) Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Redox Biol 17:367-376
RISE Consortium (2018) Impact of Insulin and Metformin Versus Metformin Alone on ?-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care 41:1717-1725

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