The Diabetes Endocrinology Research Center (DERC) at the University of Washington is one of a total 16 Diabetes Centers nationwide. The objectives of the University of Washington DERC are to: 1) provide biomedical core support to Affiliate Investigators, 2) create an environment and serve as a vehicle for interdisciplinary collaborative diabetes research, 3) sponsor an enrichment program to inform the diabetes community of new developments, and to stimulate interaction and collaboration of investigators, 4) conduct a pilot and feasibility small grant program to support diabetes research by new investigators and to provide a mechanism for established investigators in other disciplines to initiate projects in diabetes, 5) develop new research methodologies and technologies and make these available to diabetes investigators, and 6) to serve as both a focal point and an umbrella for diabetes research activities in the greater Seattle area. To accomplish these goals, the DERC is organized around seven Core units: the Administrative Core, Cellular Biology Core, Clinical Research Core, Cellular and Molecular Imaging Core, Molecular Genetics Core, Mass Spectrometry Core, and the Islet Cell and Functional Analysis Core. Through specific services provided, including new developmental work, these Cores support the research of approximately 95 Affiliate Investigators. This research covers the entire spectrum of diabetes investigation including, a) etiology and pathogenesis of type 1 diabetes, b) pathophysiology of type 2 diabetes, c) obesity and regulation of bodyweight and composition, d) clinical trials and large-scale epidemiologic studies, e) lipoprotein physiology and atherosclerosis, and f) complications of diabetes and aging. To enhance the scientific environment for diabetes research at the University of Washington and to stimulate collaboration, the DERC's Enrichment Program provides a Seminar Series, an annual Core Symposium, and a Visiting Scientist Program. As part of the Center's commitment to fostering the career development of junior faculty interested in diabetes research, each year the DERC provides $200,000 to support pilot and feasibility grants of investigators new to diabetes research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK017047-35
Application #
8040032
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O1))
Program Officer
Hyde, James F
Project Start
1996-12-01
Project End
2012-11-30
Budget Start
2010-12-01
Budget End
2011-11-30
Support Year
35
Fiscal Year
2011
Total Cost
$1,303,066
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
RISE Consortium (2018) Impact of Insulin and Metformin Versus Metformin Alone on ?-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care 41:1717-1725
Osoti, Alfred; Temu, Tecla M; Kirui, Nicholas et al. (2018) Metabolic Syndrome Among Antiretroviral Therapy-Naive Versus Experienced HIV-Infected Patients Without Preexisting Cardiometabolic Disorders in Western Kenya. AIDS Patient Care STDS 32:215-222
Sharma, Ashok; Liu, Xiang; Hadley, David et al. (2018) Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. J Autoimmun 89:90-100
Kramer, Philip A; Duan, Jicheng; Gaffrey, Matthew J et al. (2018) Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Redox Biol 17:367-376
Sharp, Seth A; Weedon, Michael N; Hagopian, William A et al. (2018) Clinical and research uses of genetic risk scores in type 1 diabetes. Curr Opin Genet Dev 50:96-102
Han, Seung Jin; Boyko, Edward J (2018) The Evidence for an Obesity Paradox in Type 2 Diabetes Mellitus. Diabetes Metab J 42:179-187
Heffron, Sean P; Lin, Bing-Xue; Parikh, Manish et al. (2018) Changes in High-Density Lipoprotein Cholesterol Efflux Capacity After Bariatric Surgery Are Procedure Dependent. Arterioscler Thromb Vasc Biol 38:245-254
Vaisar, Tomáš; Couzens, Erica; Hwang, Arnold et al. (2018) Type 2 diabetes is associated with loss of HDL endothelium protective functions. PLoS One 13:e0192616
Kang, Inkyung; Chang, Mary Y; Wight, Thomas N et al. (2018) Proteoglycans as Immunomodulators of the Innate Immune Response to Lung Infection. J Histochem Cytochem 66:241-259
Rubinow, Katya B; Houston, Barbara; Wang, Shari et al. (2018) Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasis in male mice. Asian J Androl 20:276-283

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