The Administrative Component oversees the Diabetes Research and Training Center's (DRTC) missions of excellence in inter- and multidisciplinary research, the training and development of new diabetes investigators through a Pilot &Feasibility Program, and enhancing, enriching and increasing awareness of diabetes and diabetes-related research in the greater Chicago area and nationally through the Annual Chicago Diabetes Day as well as seminars, symposia and other outreach efforts. The DRTC is an integral part of the Division of Biological Sciences of the University of Chicago. The line of authority for the DRTC extends from the Dean of the Biological Sciences Division. The DRTC leadership consists of a Director (Graeme Bell), a Director Emeritus (Donald Steiner) and three Associate Directors (Matthew Brady, Louis Philipson and Christopher Rhodes). The administrative structure of the DRTC includes the internal committees (the Steering Committee and the Biomedical Research Advisory Committee) that participate in the day to day and longer-term administration, coordination and evaluation of Center activities. It also includes an Internal Advisory Board comprised of Directors of the Institute for Translational Medicine/CTSA (Julian Solway), Chicago Center for Diabetes Translation Research (Marshall Chin), Digestive Diseases Research Core Center (Eugene Chang) and the Comprehensive Cancer Center (Michelle Le Beau) to facilitate integration of these four NlH-funded programs. The activities of the Pilot &Feasibility, and Enrichment Programs are administered through the Administrative Core. The Steering Committee reviews Pilot &Feasibility applications and then seeks advice of one or more external scientific experts as well as one internal expert. The Director may seek advice on specific issues important to the Center from an ad hoc external advisory committee as well as individual external consultants. These individuals will be nationally recognized diabetes experts and will be chosen by the Steering Committee. In summary, the Administrative Core provides efficient service to the DRTC so that it may fulfill its many missions.

Public Health Relevance

The Administrative Component provides efficient service to the DRTC so that it can fulfill its missions of excellence in research, training and development of new diabetes investigators and enhancing and increasing awareness of diabetes and diabetes-related research in the greater Chicago area.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK020595-36
Application #
8446551
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O2))
Project Start
2013-02-01
Project End
2018-01-31
Budget Start
2013-02-01
Budget End
2014-01-31
Support Year
36
Fiscal Year
2013
Total Cost
$240,877
Indirect Cost
$88,423
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Letourneau, Lisa R; Greeley, Siri Atma W (2018) Congenital Diabetes: Comprehensive Genetic Testing Allows for Improved Diagnosis and Treatment of Diabetes and Other Associated Features. Curr Diab Rep 18:46
Sanyoura, May; Philipson, Louis H; Naylor, Rochelle (2018) Monogenic Diabetes in Children and Adolescents: Recognition and Treatment Options. Curr Diab Rep 18:58
RISE Consortium (2018) Impact of Insulin and Metformin Versus Metformin Alone on ?-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care 41:1717-1725
Letourneau, Lisa R; Greeley, Siri Atma W (2018) Congenital forms of diabetes: the beta-cell and beyond. Curr Opin Genet Dev 50:25-34
Vierra, Nicholas C; Dickerson, Matthew T; Philipson, Louis H et al. (2018) Simultaneous Real-Time Measurement of the ?-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on ?-Cell Function. Methods Mol Biol 1684:73-84
Xiao, Xiangwei; Guo, Ping; Shiota, Chiyo et al. (2018) Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes. Cell Stem Cell 22:78-90.e4
Weidemann, Benjamin J; Ramsey, Kathryn Moynihan; Bass, Joseph (2018) A day in the life of chromatin: how enhancer-promoter loops shape daily behavior. Genes Dev 32:321-323
Lanning, Monica S; Carmody, David; Szczerbi?ski, ?ukasz et al. (2018) Hypoglycemia in sulfonylurea-treated KCNJ11-neonatal diabetes: Mild-moderate symptomatic episodes occur infrequently but none involving unconsciousness or seizures. Pediatr Diabetes 19:393-397
Hwang, Jessica L; Park, Soo-Young; Ye, Honggang et al. (2018) FOXP3 mutations causing early-onset insulin-requiring diabetes but without other features of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Pediatr Diabetes 19:388-392
Harris, Anastasia G; Letourneau, Lisa R; Greeley, Siri Atma W (2018) Monogenic diabetes: the impact of making the right diagnosis. Curr Opin Pediatr 30:558-567

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