Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Harding, Anne Marie S; Kusama, Nobuyoshi; Hattori, Tomonori et al. (2014) ASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95. PLoS One 9:e93797
Kusama, Nobuyoshi; Gautam, Mamta; Harding, Anne Marie S et al. (2013) Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit composition. Am J Physiol Cell Physiol 304:C89-101
Collier, Daniel M; Peterson, Zerubbabel J; Blokhin, Ilya O et al. (2012) Identification of extracellular domain residues required for epithelial Na+ channel activation by acidic pH. J Biol Chem 287:40907-14
Herlein, Judith A; Fink, Brian D; Henry, Dorlyne M et al. (2011) Mitochondrial superoxide and coenzyme Q in insulin-deficient rats: increased electron leak. Am J Physiol Regul Integr Comp Physiol 301:R1616-24
Herlein, Judy A; Fink, Brian D; Sivitz, William I (2010) Superoxide production by mitochondria of insulin-sensitive tissues: mechanistic differences and effect of early diabetes. Metabolism 59:247-57
Sivitz, William I; Yorek, Mark A (2010) Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal 12:537-77
Elliott, David E; Weinstock, Joel V (2009) Helminthic therapy: using worms to treat immune-mediated disease. Adv Exp Med Biol 666:157-66
Herlein, Judith A; Fink, Brian D; O'Malley, Yunxia et al. (2009) Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats. Endocrinology 150:46-55
Hattori, Tomonori; Chen, Jie; Harding, Anne Marie S et al. (2009) ASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac dorsal root ganglia neurons. Circ Res 105:279-86
Fink, Brian D; O'Malley, Yunxia; Dake, Brian L et al. (2009) Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells. PLoS One 4:e4250

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