Abstract

The objective of this continuation application for a Clinical Nutrition Research Unit is to develop a coherent program in nutrition for the purposes of advancing multidisciplinary clinical and laboratory research, increasing the level of nutrition teaching for medical students, physicians and other health professionals, and improving the nutrition of patients at Vanderbilt Medical Center and the public in general. The Vanderbilt CNRU has become the major resource for clinical nutrition as related to patient care, teaching and research at Vanderbilt University Medical Center. It serves as the only mechanism for coordinating the basic research generated in the nationally recognized Division of Nutrition in the Department of Biochemistry with Clinical Departments. Seven components are being developed in this collaborative program. These components are: 1. Research with human subjects and populations; 2. Laboratory Investigations; 3. Research Training; 4. Shared research facilities and services; 5. Education programs for medical students, housestaff, practicing physicians and other health care professionals; 6. Nutrition Support Services; 7. Public information services. Although direct support is provided only for research activities, the CNRU staff have developed support mechanisms for initiation and maintenance of each of the remaining components of the CNRU. Each of the CNRU components have demonstrated excellence. The plan proposed in this application will continue to expand research, education and patient care at Vanderbilt.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK026657-09
Application #
3101954
Study Section
(SRC)
Project Start
1979-09-28
Project End
1989-12-31
Budget Start
1988-01-01
Budget End
1988-12-31
Support Year
9
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37203

  Publications

Ford, Dara W; Hartman, Terryl J; Still, Christopher et al. (2014) Diet quality and body mass index are associated with health care resource use in rural older adults. J Acad Nutr Diet 114:1932-8
Tiwari, Hemant K; Patki, Amit; Lieberman, Jeffrey et al. (2011) Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study). Front Genet 2:56
Hill, Kristina E; Motley, Amy K; May, James M et al. (2009) Combined selenium and vitamin C deficiency causes cell death in guinea pig skeletal muscle. Nutr Res 29:213-9
Chen, Sheng-Song; Santomango, Tammy S; Williams, Phillip E et al. (2009) Glucagon-mediated impairments in hepatic and peripheral tissue nutrient disposal are not aggravated by increased lipid availability. Am J Physiol Endocrinol Metab 296:E1172-8
Roberts 2nd, L Jackson; Oates, John A; Linton, MacRae F et al. (2007) The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med 43:1388-93
Buchowski, M S; Majchrzak, K M; Blomquist, K et al. (2007) Energy expenditure of genuine laughter. Int J Obes (Lond) 31:131-7
Gao, Ling; Wang, Jiakun; Sekhar, Konjeti R et al. (2007) Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3. J Biol Chem 282:2529-37
Ivester, Priscilla; Roberts 2nd, L Jackson; Young, Tracey et al. (2007) Ethanol self-administration and alterations in the livers of the cynomolgus monkey, Macaca fascicularis. Alcohol Clin Exp Res 31:144-55
Chen, Sheng-Song; Zhang, Yiqun; Santomango, Tammy S et al. (2007) Glucagon chronically impairs hepatic and muscle glucose disposal. Am J Physiol Endocrinol Metab 292:E928-35
Buchowski, Maciej S; Swift, Larry L; Akohoue, Sylvie A et al. (2007) Defects in postabsorptive plasma homeostasis of fatty acids in sickle cell disease. JPEN J Parenter Enteral Nutr 31:263-8

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