The goal of the Clinical Nutrition Research Unit is to foster and expand nutrition research by the clinical science and basic science faculty at the University of Chicago and affiliated institutions. This is accomplished by offering special expertise in nutritional science, analytical services, enrichment programs, and support for young investigators seeking preliminary data for new research initiatives. The CNRU administrators and core laboratory directors are experts in clinical nutrition; nutritional assessment and support; energy utilization; carbohydrate and lipid metabolism; vitamin and mineral metabolism; nutrition and gene regulation; and stable isotope methods. This expertise is made available to other funded investigators during the design and execution of research protocols. In cases where our expertise and capabilities are beyond the resources of most institutions, such as our special program in stable isotopes, we offer these services not only to University of Chicago investigators, but to scientists throughout the USA and indeed the world. The administrative core advertises the CNRU program, works to encourage investigators to add nutritional questions to their research programs, and interacts with these investigators to minimize cost by coordinating efforts between core laboratories. In recent years, special emphasis has been placed on encouraging application of techniques of cell and molecular biology to the study &f nutritional problems. The CNRU plays a central role in the expanding nutrition program at The University of Chicago by providing a link between the strong basic biological sciences and clinical investigation and practice. Research and enrichment opportunities provided by the CNRU enhance training in nutrition for graduate students, medical students, and postdoctoral research trainees. These programs improve professional education in nutrition for medical students, physicians in-training and in-practice, and other health care workers. The CNRU works to improve the quality of nutritional information given to patients with specific nutrition-related diseases and to the general public concerned with health maintenance and disease prevention. We also encourage inclusion of clinical research programs in the many active clinical services at The University of Chicago focused on nutrition-related diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK026678-16
Application #
2137904
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1988-07-01
Project End
1999-11-30
Budget Start
1995-03-03
Budget End
1995-11-30
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Mendley, Susan R; Majkowski, Nancy L; Schoeller, Dale A (2005) Validation of estimates of total body water in pediatric dialysis patients by deuterium dilution. Kidney Int 67:2056-62
VanderLaan, Paul A; Reardon, Catherine A; Getz, Godfrey S (2004) Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators. Arterioscler Thromb Vasc Biol 24:12-22
Luke, Amy; Durazo-Arvizu, Ramon A; Rotimi, Charles N et al. (2002) Activity energy expenditure and adiposity among black adults in Nigeria and the United States. Am J Clin Nutr 75:1045-50
Kemnitz, Joseph W; Sapolsky, Robert M; Altmann, Jeanne et al. (2002) Effects of food availability on serum insulin and lipid concentrations in free-ranging baboons. Am J Primatol 57:13-9
Schoeller, D A; Jefford, G (2002) Determinants of the energy costs of light activities: inferences for interpreting doubly labeled water data. Int J Obes Relat Metab Disord 26:97-101
Reardon, C A; Blachowicz, L; White, T et al. (2001) Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 21:1011-6
Chin-Chance, C; Polonsky, K S; Schoeller, D A (2000) Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake. J Clin Endocrinol Metab 85:2685-91
Khare, S; Bissonnette, M; Wali, R et al. (1999) 1,25-dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60(c-src) and RhoA. Am J Physiol 276:G1005-15
Alverdy, J C; Hendrickson, B; Guandalini, S S et al. (1999) Perturbed bioelectrical properties of the mouse cecum following hepatectomy and starvation: the role of bacterial adherence. Shock 12:235-41;discussion 242
Wall-Alonso, E; Schoeller, D A; Schechter, L et al. (1999) Measured total energy requirements of adult patients with burns. J Burn Care Rehabil 20:329-37;discussion 328

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