Abstract

(Taken directly from the application) This proposed Core Laboratory is a consolidation of two Core laboratories, the first, Hormone/Metabolite, has been in operation since the New York Obesity Research Center (NYORC) was first funded in 1980; the second, Mass Spectroscopy, was added as a Core Laboratory in 1990. Both have been used very heavily, probably because it has been extraordinarily helpful for investigators not to have to set up methods for analyses that are more efficiently done by this Core, thereby allowing for greater productivity at lesser cost to the Users. They have been consolidated under one core with Dr. Pi-Sunyer as Director. The rationale for this is that the Mass Spectroscopy Sub-Core is at the University of Vermont and there is need for a communication center and sample-processing center for Users in New York. The User requests for service for the two Sub-Cores will come to Dr. Pi-Sunyer, who in consultation with Dr. Mathews, will prioritize use of each of the Sub-Cores and arrange for sample processing, analysis, reporting, and record keeping. Dr. Pi-Sunyer will direct the Hormone/Metabolite Sub-Core and Dr. Mathews the Mass Spectroscopy Sub-Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK026687-21
Application #
6457642
Study Section
Project Start
1980-12-01
Project End
2005-11-30
Budget Start
Budget End
Support Year
21
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
St. Luke's-Roosevelt Institute for Health Sciences
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10019

  Publications

Carli, Jayne F Martin; LeDuc, Charles A; Zhang, Yiying et al. (2018) The role of Rpgrip1l, a component of the primary cilium, in adipocyte development and function. FASEB J 32:3946-3956
Gallagher, Dympna; Rosenn, Barak; Toro-Ramos, Tatiana et al. (2018) Greater Neonatal Fat-Free Mass and Similar Fat Mass Following a Randomized Trial to Control Excess Gestational Weight Gain. Obesity (Silver Spring) 26:578-587
Rosenbaum, Michael; Goldsmith, Rochelle L; Haddad, Fadia et al. (2018) Triiodothyronine and leptin repletion in humans similarly reverse weight-loss induced changes in skeletal muscle. Am J Physiol Endocrinol Metab :
Gallagher, Dympna; Rizkalla, Bridgette (2018) The 11th International Symposium on In Vivo Body Composition Studies. Eur J Clin Nutr :
Iqbal, Niloy Jafar; Lu, Zhonglei; Liu, Shun Mei et al. (2018) Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity. JCI Insight 3:
Martin Carli, Jayne F; LeDuc, Charles A; Zhang, Yiying et al. (2018) FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications. J Lipid Res 59:1446-1460
Blumenfeld, Nicole R; Kang, Hwan June; Fenzl, Anna et al. (2018) A direct tissue-grafting approach to increasing endogenous brown fat. Sci Rep 8:7957
Ravussin, Yann; Edwin, Ethan; Gallop, Molly et al. (2018) Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding. Cell Metab 28:289-299.e5
Shechter, Ari; Kim, Elijah Wookhyun; St-Onge, Marie-Pierre et al. (2018) Blocking nocturnal blue light for insomnia: A randomized controlled trial. J Psychiatr Res 96:196-202
Sui, Lina; Danzl, Nichole; Campbell, Sean R et al. (2018) ?-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells. Diabetes 67:26-35

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