The New York Obesity Nutrition Research Center Pilot & Feasibility (PF) program provides support for basic and clinical research projects related to obesity, its etiology and complications. Since its inception 35 years ago, this program has been used successfully to 1. attract and underwrite young investigators who wish to undertake a career in obesity; 2. encourage established investigators proposing work related to obesity, outside of their usual areas of research; 3. promulgate high-risk projects that expand the NYONRC's reach into new areas of bioscience deemed likely to have relevance to aspects of our mission; 4. promote collaborative research projects among Center members and the Cores. Of the 90 prior recipients, 66 are still in obesity/nutrition academic research, four are in teaching, and seven are in industry. In the past 10 years, 21 of the recipients have been early investigators and 2 have been established investigators. To date, these 23 P/F grantees have acquired 25 grants, funded by NIH (n=16), and private foundations (n=9). The total annual direct costs for these 25 grants are nearly $3.4 M. We consider this program to be among the most important elements of the Center, and have take steps to increase the resources available to it. For this renewal we have, therefore, increased the requested budget for this program to $100k per annum of Center funds, and obtained commitments from the Deans of Columbia and Einstein for an additional $125k per annum. This $225k of annual funding will enable us to have 4-5 P&F grants (@ ~$45k per annum) active in any year. In addition, our closely integrated programs of the Berrie Center ? Berrie Frontiers Fellows and Scholars ? brings an additional $430k in per annum funding for programs focused on early stage fellows and faculty in the area of obesity, diabetes and allied metabolic disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK026687-40
Application #
9901513
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
40
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Heymsfield, S B; Peterson, C M; Bourgeois, B et al. (2018) Human energy expenditure: advances in organ-tissue prediction models. Obes Rev 19:1177-1188
Shah, Ankit; Levesque, Kiarra; Pierini, Esmeralda et al. (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery. Diabetes Obes Metab 20:1018-1023
Hayden, Kathleen M; Baker, Laura D; Bray, George et al. (2018) Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst) 10:41-48
Shechter, Ari; Schwartz, Gary J (2018) Gut-brain nutrient sensing in food reward. Appetite 122:32-35
Rosenbaum, Michael; Leibel, Rudolph L (2018) Physiological responses to leptin levels in lipodystrophy: a model for other hypoleptinemias? J Clin Invest 128:3237-3239
Toledo, Miriam; Batista-Gonzalez, Ana; Merheb, Emilio et al. (2018) Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1. Cell Metab 28:268-281.e4
Pizinger, Theresa; Kovtun, Kyle; RoyChoudhury, Arindam et al. (2018) Pilot study of sleep and meal timing effects, independent of sleep duration and food intake, on insulin sensitivity in healthy individuals. Sleep Health 4:33-39
Kissileff, H R; Herzog, M (2018) Progressive ratio (PR) schedules and the sipometer: Do they measure wanting, liking, and/or reward? A tribute to Anthony Sclafani and Karen Ackroff. Appetite 122:44-50
Pan, Xiaoyue; Schwartz, Gary J; Hussain, M Mahmood (2018) Oleoylethanolamide differentially regulates glycerolipid synthesis and lipoprotein secretion in intestine and liver. J Lipid Res 59:2349-2359
Davidson, Lance E; Yu, Wen; Goodpaster, Bret H et al. (2018) Fat-Free Mass and Skeletal Muscle Mass Five Years After Bariatric Surgery. Obesity (Silver Spring) 26:1130-1136

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