Abstract

(Taken directly from the application) The overall goal of the GRASP Molecular Biology Core has been to facilitate utilization of molecular biological techniques by center investigators and to introduce new approaches to digestive disease research. The objectives of the core are to encourage the use of state of the art molecular biological approaches for digestive disease research, to help investigators identify appropriate strategies for their own research, and to encourage established and new investigators to extend their research into digestive disease related research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034928-17
Application #
6410303
Study Section
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
17
Fiscal Year
2001
Total Cost
$200,000
Indirect Cost

  Institution

Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111

  Publications

Janoff, E N; Rubins, J B; Fasching, C et al. (2014) Pneumococcal IgA1 protease subverts specific protection by human IgA1. Mucosal Immunol 7:249-56
Mohammadi, Sina; Isberg, Ralph R (2013) Cdc42 interacts with the exocyst complex to promote phagocytosis. J Cell Biol 200:81-93
Price, Katherine E; Greene, Neil G; Camilli, Andrew (2012) Export requirements of pneumolysin in Streptococcus pneumoniae. J Bacteriol 194:3651-60
Li, Hui Joyce; Kapoor, Archana; Giel-Moloney, Maryann et al. (2012) Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine. Dev Biol 371:156-69
Schonhoff, Christopher M; Ramasamy, Umadevi; Anwer, M Sawkat (2011) Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP. Am J Physiol Gastrointest Liver Physiol 300:G364-70
Xu, K; Rajagopal, S; Klebba, I et al. (2010) The role of fibroblast Tiam1 in tumor cell invasion and metastasis. Oncogene 29:6533-42
Cullinane, Andrew R; Straatman-Iwanowska, Anna; Zaucker, Andreas et al. (2010) Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization. Nat Genet 42:303-12
Laiko, Marina; Murtazina, Rakhilya; Malyukova, Irina et al. (2010) Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. Exp Cell Res 316:657-66
Egorov, A I; Montuori Trimble, L M; Ascolillo, L et al. (2010) Recent diarrhea is associated with elevated salivary IgG responses to Cryptosporidium in residents of an eastern Massachusetts community. Infection 38:117-23
Miyoshi, Hideaki; Souza, Sandra C; Endo, Mikiko et al. (2010) Perilipin overexpression in mice protects against diet-induced obesity. J Lipid Res 51:975-82

Showing the most recent 10 out of 471 publications