Administrative Core Justification Personnel Dr. Chung Owyang will serve as the Center Director and devote 15% of his effort solely to the activities of the Peptide Center. He will coordinate all of the activities and direct the executive and scientific decisions of the Center. In addition, he will assume responsibility for implementation of the Center's goals. Dr. John A. Williams will serve as one of the Associate Directors of the Center. He serves on all of the Center's Committees and functions as the Director in the absence of Dr. Owyang. He will devote 10% of his effort to the activities of the Center with 5% salary requested in the Administrative Core and 5% in the Cell Biology and Cell Imaging Core. Dr. Juanita L. Merchant also serves as an Associate Director of the Center. She will function primarily to oversee the operations of the Core Laboratories. She also serves on some of the Center's Committees. She will devote 10% of her effort to the activities of the Center with 5% salary requested in the Administrative Core and 5% in the Molecular Biology Core. Jeffery L. Cole, M.S. serves as the Executive Administrator of the Center and, as such, is responsible for all of the personnel management and fund accounting of the Center. This includes management not only of the Center Grant itself but also involves partial management of virtually all of the other grants of the Center investigators because of the need to monitor for areas of potential overlap. His role in the Center's activities is described in detail in the narrative that follows. He will devote 100% effort to the Center. Pamela S. Varga has functioned as the Center secretary and provides support for many of the Center's functions including answering phones, supply ordering, manuscript preparation and typing of correspondence. In addition, she has functioned as an administrative assistant to Jeffery Cole during the previous funding period. She helped to keep the finances of the Center, served as the personnel officer and provided all of the staff support for the Center Seminars, the Annual Symposium and Annual Retreat. She will devote 50% effort to the Center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034933-25
Application #
8001990
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
25
Fiscal Year
2010
Total Cost
$489,792
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Dame, Michael K; Attili, Durga; McClintock, Shannon D et al. (2018) Identification, isolation and characterization of human LGR5-positive colon adenoma cells. Development 145:
Brady, Graham F; Kwan, Raymond; Ulintz, Peter J et al. (2018) Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease. Hepatology 67:1710-1725
Wang, Zhen; Ocadiz-Ruiz, Ramon; Sundaresan, Sinju et al. (2018) Isolation of Enteric Glial Cells from the Submucosa and Lamina Propria of the Adult Mouse. J Vis Exp :
Kim, D-I; Liao, J; Emont, M P et al. (2018) An OLTAM system for analysis of brown/beige fat thermogenic activity. Int J Obes (Lond) 42:939-945
Park, Min-Jung; Iyer, Sapna; Xue, Xiang et al. (2018) HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas. Gastroenterology 154:1630-1634.e3
Cho, Chun-Seok; Park, Hwan-Woo; Ho, Allison et al. (2018) Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation. Hepatology 68:1331-1346
Tsai, Yu-Hwai; Czerwinski, Michael; Wu, Angeline et al. (2018) A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture. Cell Mol Gastroenterol Hepatol 6:218-222.e7
Morhardt, Tina L; Hayashi, Atsushi; Kao, John Y et al. (2018) Regional control of regulatory immune cells in the intestine. Curr Pathobiol Rep 6:29-34
Zhou, Shi-Yi; Gillilland 3rd, Merritt; Wu, Xiaoyin et al. (2018) FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction. J Clin Invest 128:267-280
Perry, Jeffrey W; Chen, Yanhua; Speliotes, Elizabeth et al. (2018) Functional Analysis of the Dengue Virus Genome Using an Insertional Mutagenesis Screen. J Virol 92:

Showing the most recent 10 out of 757 publications