Abstract

application) The specific aims of the Gnotobiotic Core are 1. to provide germ-free or gnotobiotic rodents and conventional controls to center members as first priority, but to also provide these unique resources to investigators around the world; 2. to establish new genetic stocks and strains of rodents in an axenic, gnotobiotic or conventional status as required by research projects; 3. to provide technical assistance and isolators to maintain axenic and gnotobiotic rodent models; 4. to provide technical assistance to maintain control animals free of disease and inoculated with various gut microbiotas;5. to provide specific pathogen free conditions for maintaining production of a variety of genetically engineered rodents.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034987-16
Application #
6410307
Study Section
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
16
Fiscal Year
2001
Total Cost
$166,667
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Azcarate-Peril, M Andrea; Butz, Natasha; Cadenas, Maria Belen et al. (2018) An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome. Appl Environ Microbiol 84:
Carlson, Alexander L; Xia, Kai; Azcarate-Peril, M Andrea et al. (2018) Infant Gut Microbiome Associated With Cognitive Development. Biol Psychiatry 83:148-159
Lee, Mi Kyeong; Carnes, Megan U; Butz, Natasha et al. (2018) Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect 126:067001
Evon, D M; Amador, J; Stewart, P et al. (2018) Psychometric properties of the PROMIS short form measures in a U.S. cohort of 961 patients with chronic hepatitis C prescribed direct acting antiviral therapy. Aliment Pharmacol Ther 47:1001-1011
Jones, Roshonda B; Fodor, Anthony A; Peery, Anne F et al. (2018) An Aberrant Microbiota is not Strongly Associated with Incidental Colonic Diverticulosis. Sci Rep 8:4951
Busch, Evan L; Galanko, Joseph A; Sandler, Robert S et al. (2018) Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans. Sci Rep 8:9470
Eluri, Swathi; Cross, Raymond K; Martin, Christopher et al. (2018) Inflammatory Bowel Diseases Can Adversely Impact Domains of Sexual Function Such as Satisfaction with Sex Life. Dig Dis Sci 63:1572-1582
Dellon, Evan S; Selitsky, Sara R; Genta, Robert M et al. (2018) Gene expression-phenotype associations in adults with eosinophilic esophagitis. Dig Liver Dis 50:804-811
Rogala, Allison R; Schoenborn, Alexi A; Fee, Brian E et al. (2018) Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. Dis Model Mech 11:
Li, Feng; Kakoki, Masao; Smid, Marcela et al. (2018) Causative Effects of Genetically Determined High Maternal/Fetal Endothelin-1 on Preeclampsia-Like Conditions in Mice. Hypertension 71:894-903

Showing the most recent 10 out of 944 publications