Abstract

This application if for 5 year funding of a University of Virginia Diabetes Endocrine Research Center. Funding is requested for Administrative, Radioimmunoassay, Tissue Culture, Biomathematics, Protein and Nucleic Acid Sequencing and Molecular Biology Cores. Funding for pilot/feasibility studies is also requested.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK038942-02
Application #
3102138
Study Section
Diabetes and Digestive and Kidney Diseases Special Grants Review Committee (DDK)
Project Start
1987-07-01
Project End
1992-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Earnhardt, Richard C; Veldhuis, Johannes D; Cornett, Greg et al. (2002) Pathophysiology of hyperinsulinemia following pancreas transplantation: altered pulsatile versus Basal insulin secretion and the role of specific transplant anatomy in dogs. Ann Surg 236:480-90; discussion 490-1
Lampl, M; Birch, L; Picciano, M F et al. (2001) Child factor in measurement dependability. Am J Hum Biol 13:548-57
Straume, M; Johnson, M L; Veldhuis, J D (1998) Statistically accurate estimation of hormone concentrations and associated uncertainties: methodology, validation, and applications. Clin Chem 44:116-23
Pak, Y; Hong, Y; Kim, S et al. (1998) In vivo chiro-inositol metabolism in the rat: a defect in chiro-inositol synthesis from myo-inositol and an increased incorporation of chiro-[3H]inositol into phospholipid in the Goto-Kakizaki (G.K) rat. Mol Cells 8:301-9
Friend, K; Iranmanesh, A; Login, I S et al. (1997) Pyridostigmine treatment selectively amplifies the mass of GH secreted per burst without altering GH burst frequency, half-life, basal GH secretion or the orderliness of GH release. Eur J Endocrinol 137:377-86
Reyes-Fuentes, A; Chavarria, M E; Aguilera, G et al. (1997) Deconvolution analysis of bioassayable LH secretion and half-life in men with idiopathic oligoasthenospermia. Int J Androl 20:118-25
Veldhuis, J D (1996) Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. Pediatr Nephrol 10:304-17
Pincus, S M; Mulligan, T; Iranmanesh, A et al. (1996) Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males. Proc Natl Acad Sci U S A 93:14100-5
van den Berg, G; Veldhuis, J D; Frolich, M et al. (1996) An amplitude-specific divergence in the pulsatile mode of growth hormone (GH) secretion underlies the gender difference in mean GH concentrations in men and premenopausal women. J Clin Endocrinol Metab 81:2460-7
Zwart, A D; Urban, R J; Odell, W D et al. (1996) Contrasts in the gonadotropin-releasing hormone dose-response relationships for luteinizing hormone, follicle-stimulating hormone and alpha-subunit release in young versus older men: appraisal with high-specificity immunoradiometric assay and deconvolutio Eur J Endocrinol 135:399-406

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