Abstract

THE PROPOSED SPECIFIC AIMS OF THE CELL BIOLOGY CORE ARE TO PROVIDE: 1. Space, supplies, and access to sophisticated equipment used in morphology, cell culture, and immunology 2. Specific training and supervision for utilizing specialized techniques and equipment 3. Expert consultative services in research design 4. Efficient coordinated acquisition of data and data interpretation 5. Enrichment courses in basic concepts in molecular cell biology, nutrition interaction with Gl immunology. Proposed core services provided by the NORC-H Cell Biology Core include: 1. Individual assistance, training and supervision for using specialized techniques and equipment. 2. Consultative services for morphological, immunological and tissue culture experiments. 3. Research instrumentation, technical support, and expertise in morphology, immunology and cell culture. 4. Data acquisition, analysis and interpretation. 5. Formal courses on basic concepts in molecular cell biology, and nutrition interaction with Gl immunology (at an affordable cost).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK040561-18
Application #
8715764
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
18
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Patel, Dhiren K; Stanford, Fatima Cody (2018) Safety and tolerability of new-generation anti-obesity medications: a narrative review. Postgrad Med 130:173-182
Triant, Virginia A; Perez, Jeremiah; Regan, Susan et al. (2018) Cardiovascular Risk Prediction Functions Underestimate Risk in HIV Infection. Circulation 137:2203-2214
Nickerson, K P; Senger, S; Zhang, Y et al. (2018) Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue. EBioMedicine 31:92-109
Fujisaka, Shiho; Avila-Pacheco, Julian; Soto, Marion et al. (2018) Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites. Cell Rep 22:3072-3086
Jacobson, Sandra W; Carter, R Colin; Molteno, Christopher D et al. (2018) Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Alcohol Clin Exp Res 42:1315-1326
Winje, Brita Askeland; Kvestad, Ingrid; Krishnamachari, Srinivasan et al. (2018) Does early vitamin B12 supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania. BMJ Open 8:e018962
Plessow, Franziska; Marengi, Dean A; Perry, Sylvia K et al. (2018) Effects of Intranasal Oxytocin on the Blood Oxygenation Level-Dependent Signal in Food Motivation and Cognitive Control Pathways in Overweight and Obese Men. Neuropsychopharmacology 43:638-645
Jacob, Jaison; Ngo, Debby; Finkel, Nancy et al. (2018) Application of Large-Scale Aptamer-Based Proteomic Profiling to Planned Myocardial Infarctions. Circulation 137:1270-1277
Fourman, Lindsay T; Czerwonka, Natalia; Shaikh, Sofia D et al. (2018) Insulin-like growth factor 1 inversely relates to monocyte/macrophage activation markers in HIV. AIDS 32:927-932
Srinivasa, Suman; Lu, Michael T; Fitch, Kathleen V et al. (2018) Epicardial adipose tissue volume and cardiovascular risk indices among asymptomatic women with and without HIV. Antivir Ther 23:1-9

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