It is proposed to establish an interdisciplinary OBESITY/NUTRITION RESEARCH CENTER (ONRC) at the UNIVERSITY OF VERMONT (UVM) to be known as the SIMS OBESITY/NUTRITION CENTER, to enrich and expand an ongoing, program of excellence in obesity research in the Endocrinology, Metabolism and Nutrition Division (""""""""Metabolic Unit"""""""") of the UVM College of Medicine and to honor its founder and his many contributions to our knowledge of this disease.
The specific aims of this ONRC will be to (1) formalize our program and extend it across the university as a Center of Excellence, (2) enrich and expand the scope of the clinical research program, stable isotope program and strengthen its molecular biology focus, (3) promote greater interdisciplinary approaches to this research effort, (4) help support state-of-the-art equipment and facilities required to stay at the cutting edge of obesity/nutrition research, and (5) support promising young investigators to become established and established investigators from other fields of endeavor with unique talents or novel ideas who are interested in obesity/nutrition research with Pilot and Feasibility Projects to collect preliminary data to compete for independent funding. In addition, it is proposed to support a Named New Investigator, to help in attract and recruit new faculty to the center, and an Enrichment Program to (1) support visiting scientists, (2) sponsor a yearly review and research forum, (3) support the educational efforts of the faculty and for the faculty to lean new techniques and develop new collaborations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK046188-02
Application #
3102191
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1992-09-30
Project End
1997-09-29
Budget Start
1993-09-30
Budget End
1994-09-29
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Ballor, D L; Harvey-Berino, J R; Ades, P A et al. (1996) Contrasting effects of resistance and aerobic training on body composition and metabolism after diet-induced weight loss. Metabolism 45:179-83
Ballor, D L; Harvey-Berino, J R; Ades, P A et al. (1996) Decrease in fat oxidation following a meal in weight-reduced individuals: a possible mechanism for weight recidivism. Metabolism 45:174-8
Goodyear, L J; Hirshman, M F; Napoli, R et al. (1996) Glucose ingestion causes GLUT4 translocation in human skeletal muscle. Diabetes 45:1051-6
Himms-Hagen, J; Cui, J; Danforth Jr, E et al. (1994) Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats. Am J Physiol 266:R1371-82