Abstract

The objectives of this core are to provide: 1. A service facility that wil utilize investigator-derived DNA constructs to create founder transgenic and gene knockout mice that can be used to address questions relevant to obesity and nutrition research; 2. Consultations to obesity and nutrition researchers regarding general aspects of transgenic and gene knockout work, the use of tissue-specific promoters, the generation of transgenic and gene knockout constructs, and the establishment and monitoring of genetically modified mouse colonies; and 3. Training in methods required for the generation of transgenic and gene knockout DNA constructs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK046200-06
Application #
6239095
Study Section
Project Start
1997-09-30
Project End
1998-09-29
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111

  Publications

Mínguez-Alarcón, Lidia; Afeiche, Myriam C; Williams, Paige L et al. (2018) Hair mercury (Hg) levels, fish consumption and semen parameters among men attending a fertility center. Int J Hyg Environ Health 221:174-182
Nassan, Feiby L; Chiu, Yu-Han; Vanegas, Jose C et al. (2018) Intake of protein-rich foods in relation to outcomes of infertility treatment with assisted reproductive technologies. Am J Clin Nutr 108:1104-1112
Arvizu, Mariel; Afeiche, Myriam C; Hansen, Susanne et al. (2018) Fat intake during pregnancy and risk of preeclampsia: a prospective cohort study in Denmark. Eur J Clin Nutr :
Harris, H R; Eke, A C; Chavarro, J E et al. (2018) Fruit and vegetable consumption and risk of endometriosis. Hum Reprod 33:715-727
Kong, Xingxing; Yao, Ting; Zhou, Peng et al. (2018) Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metab 28:631-643.e3
Nisa, Hoirun; Qi, Kevin H T; Leng, Junhong et al. (2018) The Circadian Rhythm-Related MTNR1B Genotype, Gestational Weight Gain, and Postpartum Glycemic Changes. J Clin Endocrinol Metab 103:2284-2290
Chiu, Yu-Han; Williams, Paige L; Gillman, Matthew W et al. (2018) Association Between Pesticide Residue Intake From Consumption of Fruits and Vegetables and Pregnancy Outcomes Among Women Undergoing Infertility Treatment With Assisted Reproductive Technology. JAMA Intern Med 178:17-26
Sun, Dianjianyi; Li, Xiang; Heianza, Yoriko et al. (2018) History of Asthma From Childhood and Arterial Stiffness in Asymptomatic Young Adults: The Bogalusa Heart Study. Hypertension 71:928-936
Ross, Rachel A; Leon, Silvia; Madara, Joseph C et al. (2018) PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse. Elife 7:
Fadelu, Temidayo; Zhang, Sui; Niedzwiecki, Donna et al. (2018) Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol 36:1112-1120

Showing the most recent 10 out of 876 publications