Abstract

The objectives of this core are to assist Boston Obesity Center members by: 1. Preparing human and experimental animal fat cells and preadipocytes and products of these cells including DNA, RNA, protein, and conditioned medium; 2. Providing consultative advice about experimental design and methods involving these cells and products; 3. Teaching investigators and members of their laboratories about the preparation of fat cells, preadiopocytes, and products of these cells from humans and experimental animals; and 4. Supporting the continuing development of the Adipose Tissue Study group fostering collaborative links among investigators in adipocyte biology, and continuing to provide assistance to investigators new to the field.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK046200-06
Application #
6239096
Study Section
Project Start
1997-09-30
Project End
1998-09-29
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111

  Publications

Maldonado-Cárceles, Ana B; Mínguez-Alarcón, Lidia; Mendiola, Jaime et al. (2018) Meat intake in relation to semen quality and reproductive hormone levels among young men in Spain. Br J Nutr :1-10
Han, Liyuan; Duan, Donghui; Zhang, Shuang et al. (2018) Effects of the interaction between glycated haemoglobin genetic risk score and postpartum weight reduction on glycaemic changes: A gene-weight interaction analysis. Diabetes Obes Metab 20:2733-2739
Jager, Mike; Lee, Mi-Jeong; Li, Chendi et al. (2018) Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue. PLoS One 13:e0197777
Cardamone, Maria Dafne; Tanasa, Bogdan; Cederquist, Carly T et al. (2018) Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Mol Cell 69:757-772.e7
Martin Carli, Jayne F; LeDuc, Charles A; Zhang, Yiying et al. (2018) FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications. J Lipid Res 59:1446-1460
Buendia, Justin R; Li, Yanping; Hu, Frank B et al. (2018) Regular Yogurt Intake and Risk of Cardiovascular Disease Among Hypertensive Adults. Am J Hypertens 31:557-565
Sun, Dianjianyi; Heianza, Yoriko; Li, Xiang et al. (2018) Genetic, epigenetic and transcriptional variations at NFATC2IP locus with weight loss in response to diet interventions: The POUNDS Lost Trial. Diabetes Obes Metab 20:2298-2303
Goni, Leticia; Sun, Dianjianyi; Heianza, Yoriko et al. (2018) Macronutrient-specific effect of the MTNR1B genotype on lipid levels in response to 2 year weight-loss diets. J Lipid Res 59:155-161
Xu, Jie; Bartolome, Christopher L; Low, Cho Shing et al. (2018) Genetic identification of leptin neural circuits in energy and glucose homeostases. Nature 556:505-509
Gaskins, Audrey J; Chavarro, Jorge E (2018) Diet and fertility: a review. Am J Obstet Gynecol 218:379-389

Showing the most recent 10 out of 876 publications