Abstract

The overall theme of the Metabolic Core lab is to support investigation of insulin resistance, obesity, and inflammation from a cellular/molecular perspective. The Metabolic Core provides consultation and analysis of insulin signaling, hormone assays, qPCR, insulin clamping (mice, rats), and cell based assays of cytokines and adipokines tailored to the investigators needs. Over the last grant period the Metabolic Core has developed expertise in multiplex based cytokine analysis. Most recently the Metabolic Core received NIH funding to purchase a Seahorse XF24-3 extracellular flux analyzer to allow us to begin to interrogate mitochondrial function.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK048520-16
Application #
8016442
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (M2))
Project Start
2010-08-01
Project End
2015-07-31
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
16
Fiscal Year
2010
Total Cost
$223,797
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Bellows, Laura L; McCloskey, Morgan; Clark, Lauren et al. (2018) HEROs: Design of a Mixed-Methods Formative Research Phase for an Ecocultural Intervention to Promote Healthy Eating and Activity Behaviors in Rural Families With Preschoolers. J Nutr Educ Behav :
Erlandson, Kristine M; Lake, Jordan E; Sim, Myung et al. (2018) Bone Mineral Density Declines Twice as Quickly Among HIV-Infected Women Compared With Men. J Acquir Immune Defic Syndr 77:288-294
Kuwabara, Masanari; Hisatome, Ichiro; Niwa, Koichiro et al. (2018) Uric Acid Is a Strong Risk Marker for Developing Hypertension From Prehypertension: A 5-Year Japanese Cohort Study. Hypertension 71:78-86
Peppler, Willem T; Townsend, Logan K; Knuth, Carly M et al. (2018) Subcutaneous inguinal white adipose tissue is responsive to, but dispensable for, the metabolic health benefits of exercise. Am J Physiol Endocrinol Metab 314:E66-E77
Diab, Liliane; Krebs, Nancy F (2018) Vitamin Excess and Deficiency. Pediatr Rev 39:161-179
Lake, Jordan E; Li, Xiuhong; Palella Jr, Frank J et al. (2018) Metabolic health across the BMI spectrum in HIV-infected and HIV-uninfected men. AIDS 32:49-57
Jovanovich, Anna; Isakova, Tamara; Block, Geoffrey et al. (2018) Deoxycholic Acid, a Metabolite of Circulating Bile Acids, and Coronary Artery Vascular Calcification in CKD. Am J Kidney Dis 71:27-34
Hill, James M; O'Leary, Joseph (2018) Generalized transformations and coordinates for static spherically symmetric general relativity. R Soc Open Sci 5:171109
Estrada, Andrea Lee; Hudson, William Max; Kim, Paul Y et al. (2018) Short-term changes in diet composition do not affect in vivo hepatic protein synthesis in rats. Am J Physiol Endocrinol Metab 314:E241-E250
Bjornstad, Petter; Cree-Green, Melanie; Baumgartner, Amy et al. (2018) Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtform Pediatr Diabetes 19:436-442

Showing the most recent 10 out of 756 publications