The overarching goals of the Administrative and Resource Access Core (ARAC) are to coordinate and integrate all activities of the Center, including Core reporting, P/F administration and enrichment activities. These organizational goals include promoting awareness of and interest in digestive disease related research through several linked mechanisms. First, the ARAC is committed to fostering and encouraging collaborative, trans-disciplinary research activities across the WU community through biomedical cores that provide enabling technology to its members with the goal of expanding research capacity. Secondly, the ARAC is committed to attracting investigators from other disciplines into digestive disease research and to promote these interests in trainees and junior faculty through an extensive Enrichment Program that includes research seminars, workshops and dedicated mentoring. Thirdly, the ARAC is committed to identifying and nurturing the careers of junior faculty interested in digestive disease through a rigorously peer reviewed Pilot/Feasibility Program that provides seed support for the most promising work. Fourthly, the ARAC is committed to promoting and enhancing synergies, among other NIDDK funded centers locally (DRC, NORC) as well as other DDRCCs regionally (through the Midwest Alliance)and nationally.
The Specific Aims for ARAC include:(1)Promote and enhance scientific dialog and collaboration centered on digestive disease among members spanning multiple departments and Centers, guided by a Steering Committee;(2) Organize and align core laboratories and services to provide state-of-the-art services and specialized expertise in line with members' needs;(3)0versee resource allocation through shared institutional Cores, guided by an Internal Executive Committee;(4)Review and align Research Base membership, guided by an Internal Executive Committee;(5)Assure stewardship of DDRCC resources in line with the needs of the Research Base and guided by an External Advisory Board;(6)Coordinate successful enrichment activities and promote career advancement of fellows and junior faculty interested in digestive disease research;(7)Assure dialog through web based communication, with other DDRCCs particularly those in the Midwest Alliance.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK052574-18
Application #
9197986
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2016-12-01
Budget End
2017-11-30
Support Year
18
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Wang, Xuanchuan; Xu, Min; Jia, Jianluo et al. (2018) CD47 blockade reduces ischemia/reperfusion injury in donation after cardiac death rat kidney transplantation. Am J Transplant 18:843-854
Ingle, Harshad; Peterson, Stefan T; Baldridge, Megan T (2018) Distinct Effects of Type I and III Interferons on Enteric Viruses. Viruses 10:
Biddy, Brent A; Kong, Wenjun; Kamimoto, Kenji et al. (2018) Single-cell mapping of lineage and identity in direct reprogramming. Nature 564:219-224
Platt, Derek J; Smith, Amber M; Arora, Nitin et al. (2018) Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice. Sci Transl Med 10:
Strubberg, Ashlee M; Veronese Paniagua, Daniel A; Zhao, Tingting et al. (2018) The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells. Stem Cell Reports 11:410-424
Patel, A; Hasak, S; Nix, B D et al. (2018) Genetic risk factors for perception of symptoms in GERD: an observational cohort study. Aliment Pharmacol Ther 47:289-297
Hibberd, Timothy J; Feng, Jing; Luo, Jialie et al. (2018) Optogenetic Induction of Colonic Motility in Mice. Gastroenterology 155:514-528.e6
Mayer, Allyson L; Zhang, Yiming; Feng, Emily H et al. (2018) Enhanced Hepatic PPAR? Activity Links GLUT8 Deficiency to Augmented Peripheral Fasting Responses in Male Mice. Endocrinology 159:2110-2126
Wardill, Hannah R; Van Sebille, Ysabella Z A; Ciorba, Matthew A et al. (2018) Prophylactic probiotics for cancer therapy-induced diarrhoea: a meta-analysis. Curr Opin Support Palliat Care 12:187-197
Osaki, Luciana H; Bockerstett, Kevin A; Wong, Chun Fung et al. (2018) Interferon-? directly induces gastric epithelial cell death and is required for progression to metaplasia. J Pathol :

Showing the most recent 10 out of 899 publications