Overall Component The overarching theme of the Nutrition Obesity Research Center (NORC) at the University of North Carolina at Chapel Hill is Trans-Disciplinary Nutrition Research: From Molecules to Public Health. The NORC adapts and translates expertise in community/population-based and clinical studies to facilitate the transfer of ideas and information to the laboratory, while at the same time helping to translate ideas from the laboratory into new hypotheses for studies at the clinical and community level. We propose an Administrative Core and five Scientific Cores: Diet and Physical Activity in Human Populations (DPAC), Communication for Health Applications and Interventions (CHAI), Metabolic Molecular Phenotyping (MMP) and Animal Metabolism Phenotyping (AMP), all of which are ongoing successful cores already providing exceptional services to NORC members. The Nutrigenetics Core (NGx) is a new developmental core that will get seed funding to develop services that will help public health and other researchers access nutrigenetics methods for use in their research. Our record of success during the last funding period is substantial. NORC activities have resulted in significant increases in the number and productivity of nutrition and obesity investigators at UNC, the funding for nutrition and obesity research, and the understanding of the importance of nutrition and obesity among researchers, clinicians, and the general public. The NORC has 130 member scientists from 36 different departments and divisions of UNC. They have exceptional research funding, having been awarded $179.8 million in nutrition and obesity grants during the last five years ($40.6 million in 2015 alone (first quarter)). Of this total, 91% of the funding was from federal grants ($163.3 million, NIH, USDA, CDC, DOD) with $41.7 million from the NIDDK. Our research base members have an exceptional publication record; with 859 peer- reviewed publications that are directly related to the support they received from the NORC.

Public Health Relevance

The University of North Carolina Nutrition Obesity Research Center (UNC NORC) focuses on Trans- Disciplinary Nutrition Research: From Molecules to Public Health. We propose an Administrative Core and five Scientific Core Facilities: 'Diet and Physical Activity in Human Populations (DPAC),' 'Nutrition Communication for Health Applications and Interventions (CHAI),' 'Metabolic Molecular Phenotyping (MMP)', 'Animal Metabolism Phenotyping (AMP) and Nutrigenetics (NGx)

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK056350-20
Application #
9889109
Study Section
Special Emphasis Panel (ZDK1)
Program Officer
Evans, Mary
Project Start
1999-09-30
Project End
2021-03-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
20
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Nutrition
Type
Schools of Public Health
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Xu, Xiaoyue; Parker, Deborah; Shi, Zumin et al. (2018) Dietary Pattern, Hypertension and Cognitive Function in an Older Population: 10-Year Longitudinal Survey. Front Public Health 6:201
McClain, Kathleen M; Bradshaw, Patrick T; Khankari, Nikhil K et al. (2018) Fish/shellfish intake and the risk of head and neck cancer. Eur J Cancer Prev :
Hirsch, Katie R; Tweedell, Andrew J; Kleinberg, Craig R et al. (2018) The Influence of Habitual Protein Intake on Body Composition and Muscular Strength in Career Firefighters. J Am Coll Nutr 37:620-626
Sullivan, E Madison; Pennington, Edward Ross; Sparagna, Genevieve C et al. (2018) Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. J Biol Chem 293:466-483
Du, Wenwen; Wang, Huijun; Wang, Zhihong et al. (2018) Dietary vitamin a intake among Chinese adults: findings from CNTCS2015. Nutr J 17:60
Dunford, E K; Popkin, B M (2018) 37 year snacking trends for US children 1977-2014. Pediatr Obes 13:247-255
Jacobson, Sandra W; Carter, R Colin; Molteno, Christopher D et al. (2018) Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Alcohol Clin Exp Res 42:1315-1326
Dunford, Elizabeth K; Taillie, Lindsey Smith; Miles, Donna R et al. (2018) Non-Nutritive Sweeteners in the Packaged Food Supply-An Assessment across 4 Countries. Nutrients 10:
Vaughn, Amber E; Martin, Chantel L; Ward, Dianne S (2018) What matters most - what parents model or what parents eat? Appetite 126:102-107
Truax, Agnieszka D; Chen, Liang; Tam, Jason W et al. (2018) The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. Cell Host Microbe 24:364-378.e6

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