The molecular biology core provides cost-effective access to tools and services that are essential for modern molecular biology;it also provides training and technology to enable the Boston area diabetes research community to employ advanced gene discovery and analysis approaches. The services offered or planned by the molecular biology core lie in the areas of DNA sequencing, oligonucleotide synthesis, gene expression profiling, siRNA screening and automation support. The molecular biology core is also the docking core for BADERC investigator collaborations with the Broad Institute on topics in diabetes research. The molecular biology core with provide the administrative support for steering committee decisions and will guide investigators to the appropriate investigators and technology platforms at the Broad.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK057521-12
Application #
8249922
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
12
Fiscal Year
2011
Total Cost
$193,250
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Ross, Rachel A; Leon, Silvia; Madara, Joseph C et al. (2018) PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse. Elife 7:
Berkowitz, Seth A; Karter, Andrew J; Corbie-Smith, Giselle et al. (2018) Food Insecurity, Food ""Deserts,"" and Glycemic Control in Patients With Diabetes: A Longitudinal Analysis. Diabetes Care 41:1188-1195
Syed, Ismail; Lee, Jennifer; Moraes-Vieira, Pedro M et al. (2018) Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab 27:419-427.e4
Vujic, Ana; Lerchenmüller, Carolin; Wu, Ting-Di et al. (2018) Exercise induces new cardiomyocyte generation in the adult mammalian heart. Nat Commun 9:1659
Fulzele, Keertik; Dedic, Christopher; Lai, Forest et al. (2018) Loss of Gs? in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity. Bone 117:138-148
Battistone, Maria A; Nair, Anil V; Barton, Claire R et al. (2018) Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells. J Am Soc Nephrol 29:545-556
Cheung, Pui W; Terlouw, Abby; Janssen, Sam Antoon et al. (2018) Inhibition of non-receptor tyrosine kinase Src induces phosphoserine 256-independent aquaporin-2 membrane accumulation. J Physiol :
Karim, Lamya; Moulton, Julia; Van Vliet, Miranda et al. (2018) Bone microarchitecture, biomechanical properties, and advanced glycation end-products in the proximal femur of adults with type 2 diabetes. Bone 114:32-39
Kolar, Matthew J; Nelson, Andrew T; Chang, Tina et al. (2018) Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements. Anal Chem 90:5358-5365
Todd, William D; Fenselau, Henning; Wang, Joshua L et al. (2018) A hypothalamic circuit for the circadian control of aggression. Nat Neurosci 21:717-724

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