Abstract

The Human Phenotyping Core builds upon a strong research base in the clinical sciences encompassing a wide range of research techniques. The existing tools will be used to explore new avenues of multi-disciplinary clinical research in the area of Nutritional Programming. New data provides substantial evidence that the most common chronic diseases in the United States may have their origins in the regulation of gene expression and functioning vis-a-vis epigenomic regulation. Now, more than ever, the precise quantification of specific clinical phenotypes is essential for the application of genomic technologies and basic science discoveries to the human condition. Also, multi-disciplinary teams are needed to investigate complex, integrated biological phenomena. This Core will integrate established techniques with cutting edge measurements of in-situ biochemistry, ingestive behavior and physical activity to foster research in the area of nutritional programming.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-04
Application #
7669115
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
4
Fiscal Year
2008
Total Cost
$408,538
Indirect Cost

  Institution

Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808

  Publications

Rose, Meredith H; Streisand, Randi; Aronow, Laura et al. (2018) Preliminary Feasibility and Acceptability of the Remote Food Photography Method for Assessing Nutrition in Young Children with Type 1 Diabetes. Clin Pract Pediatr Psychol 6:270-277
Broskey, Nicholas T; Obanda, Diana N; Burton, Jeffrey H et al. (2018) Skeletal muscle ceramides and daily fat oxidation in obesity and diabetes. Metabolism 82:118-123
Broskey, Nicholas T; Tam, Charmaine S; Sutton, Elizabeth F et al. (2018) Metabolic inflexibility in women with PCOS is similar to women with type 2 diabetes. Nutr Metab (Lond) 15:75
Marlatt, Kara L; White, Ursula A; Beyl, Robbie A et al. (2018) Role of resistant starch on diabetes risk factors in people with prediabetes: Design, conduct, and baseline results of the STARCH trial. Contemp Clin Trials 65:99-108
Staiano, Amanda E; Allen, Andrew T; Fowler, Whitney et al. (2018) State Licensing Regulations on Screen Time in Childcare Centers: An Impetus for Participatory Action Research. Prog Community Health Partnersh 12:101-109
Forney, Laura A; Stone, Kirsten P; Wanders, Desiree et al. (2018) The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. Appl Physiol Nutr Metab 43:123-130
Katzmarzyk, Peter T; Martin, Corby K; Newton Jr, Robert L et al. (2018) Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL): Rationale, design and baseline characteristics. Contemp Clin Trials 67:1-10
Fazzino, Tera L; Martin, Corby K; Forbush, Kelsie (2018) The Remote Food Photography Method and SmartIntake App for the Assessment of Alcohol Use in Young Adults: Feasibility Study and Comparison to Standard Assessment Methodology. JMIR Mhealth Uhealth 6:e10460
Most, Jasper; Gilmore, L Anne; Smith, Steven R et al. (2018) Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance. Am J Physiol Endocrinol Metab 314:E396-E405
Myers, Candice A; Martin, Corby K; Apolzan, John W (2018) Food cravings and body weight: a conditioning response. Curr Opin Endocrinol Diabetes Obes 25:298-302

Showing the most recent 10 out of 759 publications