Abstract

The Animal Models and Phenotyping Core will provide support for CNRU and other investigators in two major areas; the provision of new animal models through either transgenic or gene targeting techniques and the phenotypic characterization of animals for behavioral characteristics, body composition or metabolic parameters relevant to the overall goal of the CNRU in investigating the effects of nutritional programming on the development of obesity/diabetes. The Core will provide direct services and/or training for CNRU investigators and other faculty. The Core Director (David York) and Assoc. Director (Randy Mynatt) have long experience in animal physiology working with all the behavioral and metabolic phenotyping methods and the transgenic/gene targeting procedures that are included in this Core. Both user fees and institutional support will fund the Core. The Core staff will also work with faculty to develop additional established procedures or to develop new innovative methods that are relevant to the overall goal of the CNRU and that will enhance the productivity and research quality of the investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-04
Application #
7669117
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
4
Fiscal Year
2008
Total Cost
$307,161
Indirect Cost

  Institution

Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808

  Publications

Sarzynski, Mark A; Ruiz-Ramie, Jonathan J; Barber, Jacob L et al. (2018) Effects of Increasing Exercise Intensity and Dose on Multiple Measures of HDL (High-Density Lipoprotein) Function. Arterioscler Thromb Vasc Biol 38:943-952
Peaceman, Alan M; Clifton, Rebecca G; Phelan, Suzanne et al. (2018) Lifestyle Interventions Limit Gestational Weight Gain in Women with Overweight or Obesity: LIFE-Moms Prospective Meta-Analysis. Obesity (Silver Spring) 26:1396-1404
Yu, Sangho; François, Marie; Huesing, Clara et al. (2018) The Hypothalamic Preoptic Area and Body Weight Control. Neuroendocrinology 106:187-194
Burke, Susan J; Batdorf, Heidi M; Martin, Thomas M et al. (2018) Liquid Sucrose Consumption Promotes Obesity and Impairs Glucose Tolerance Without Altering Circulating Insulin Levels. Obesity (Silver Spring) 26:1188-1196
Herion, Nils Janis; Kruger, Claudia; Staszkiewicz, Jaroslaw et al. (2018) Embryonic cell migratory capacity is impaired upon exposure to glucose in vivo and in vitro. Birth Defects Res :
Katzmarzyk, Peter T; Most, Jasper; Redman, Leanne M et al. (2018) Energy expenditure and substrate oxidation in White and African American young adults without obesity. Eur J Clin Nutr 72:920-922
Hsueh, Wen-Chi; Bennett, Peter H; Esparza-Romero, Julian et al. (2018) Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA. Ann Hum Genet 82:287-299
Yu, Yongmei; Mendoza, Tamra M; Ribnicky, David M et al. (2018) An Extract of Russian Tarragon Prevents Obesity-Related Ectopic Lipid Accumulation. Mol Nutr Food Res 62:e1700856
Yan, Hao; Carmichael, Owen; Paul, Debashis et al. (2018) Estimating fiber orientation distribution from diffusion MRI with spherical needlets. Med Image Anal 46:57-72
Obanda, Diana; Page, Ryan; Guice, Justin et al. (2018) CD Obesity-Prone Rats, but not Obesity-Resistant Rats, Robustly Ferment Resistant Starch Without Increased Weight or Fat Accretion. Obesity (Silver Spring) 26:570-577

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