The overall goal of the Enrichment Program of the Digestive Health Center (DHC) is to advance digestive disease research by creating a forum where investigators will present new research findings, learn about new technologies, and pursue new collaborations. The Director of the Program and DHC leaders pursue this goal with four complementary aims. In the first aim ?to promote knowledge sharing through a weekly seminar and workshop series,? the Program sponsors a series of highly interactive seminars and presentations by investigators from the academic health center and extramural scientists who are leaders in digestive disease research. These seminars also include technology-centered workshops that are given by Core directors and staff. Presenters receive timely feedback and suggestions on their experimental approaches and emerging technologies. Seminars and workshops represent a nidus of collaboration and knowledge-sharing among participants. In the second aim ?to increase collaboration with other academic units by joint educational programs,? the Program Director seeks opportunities to partner with focus groups or study groups to fertilize ongoing interests in the field, with three recurring meetings with: 1) the ?Fluxes and Barriers? group of intestinal physiologists; 2) the ?Endoderm Club,? which focuses on organoid systems to model human disease; and 3) the ?Distinguished Speaker Program? with the Division of Developmental Biology to expose DHC investigators and trainees to the most successful scientists in the field. In the third aim ?to hold an annual scientific symposium to highlight digestive disease discoveries,? the DHC combines the annual visit of the External Advisory Board with a day devoted to digestive disease research via a highly subscribed symposium featuring a distinguished speaker and a scientific forum for the presentation of posters reporting novel findings by trainees and junior faculty. And in the fourth aim, ?to increase visibility for digestive disease research in the Academic Health Center? the Program publishes a quarterly Newsletter that is circulated throughout the academic health center to share information on upcoming seminars, accomplishments and awards of DHC investigators, and updates of Core services.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK078392-14
Application #
9951047
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
14
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Soini, Tea; Pihlajoki, Marjut; Andersson, Noora et al. (2018) Transcription factor GATA6: a novel marker and putative inducer of ductal metaplasia in biliary atresia. Am J Physiol Gastrointest Liver Physiol 314:G547-G558
Kelly, Daniel; Kotliar, Michael; Woo, Vivienne et al. (2018) Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI Insight 3:
Haberman, Yael; BenShoshan, Marina; Di Segni, Ayelet et al. (2018) Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. Inflamm Bowel Dis 24:346-360
Ayalon, Itay; Shen, Hui; Williamson, Lauren et al. (2018) Sepsis Induces Adipose Tissue Browning in Nonobese Mice But Not in Obese Mice. Shock 50:557-564
Amarachintha, Surya; Harmel-Laws, Eleana; Steinbrecher, Kris A (2018) Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens. Sci Rep 8:1521
Patterson, Andrew R; Endale, Mehari; Lampe, Kristin et al. (2018) Gimap5-dependent inactivation of GSK3? is required for CD4+ T cell homeostasis and prevention of immune pathology. Nat Commun 9:430
Jose, S; Abhyankar, M M; Mukherjee, A et al. (2018) Leptin receptor q223r polymorphism influences neutrophil mobilization after Clostridium difficile infection. Mucosal Immunol 11:947-957
Goodman, Michael Aaron; Arumugam, Paritha; Pillis, Devin Marie et al. (2018) Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential. J Virol 92:
Kim, Paul; Piraino, Giovanna; O'Connor, Michael et al. (2018) Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPK?1-Independent Manner. Shock 49:277-287
Lee, Kang Kug; McCauley, Heather A; Broda, Taylor R et al. (2018) Human stomach-on-a-chip with luminal flow and peristaltic-like motility. Lab Chip 18:3079-3085

Showing the most recent 10 out of 543 publications