Abstract

The overall objective of the Administrative Component of the George M. O'Brien Kidney Center at Yale is to ensure that Center functions and, activities are optimized to fulfill the overarching goal of facilitating basic, translational and clinical research that will advance the prevention and treatment of kidney diseases. To achieve this objective, the Administrative Component will pursue the following specific aims: 1. Provide financial management of the Center 2. Organize and coordinate activities of all administrative committees 3. Monitor core use and services, and allocate resources among Center cores 4. Facilitate communication with kidney research community including maintenance of Center website 5. Manage Pilot and Feasibility Grant Program 6. Organize and coordinate Enrichment Program

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK079310-07
Application #
8734392
Study Section
Special Emphasis Panel (ZDK1-GRB-6)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
7
Fiscal Year
2014
Total Cost
$333,450
Indirect Cost
$133,180

  Institution

Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Lausecker, Franziska; Tian, Xuefei; Inoue, Kazunori et al. (2018) Vinculin is required to maintain glomerular barrier integrity. Kidney Int 93:643-655
Knauf, Felix; Velazquez, Heino; Pfann, Victoria et al. (2018) Characterization of renal NaCl and oxalate transport in Slc26a6-/- mice. Am J Physiol Renal Physiol :
Silva, Luciane M; Jacobs, Damon T; Allard, Bailey A et al. (2018) Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells. Sci Rep 8:4985
Daga, Ankana; Majmundar, Amar J; Braun, Daniela A et al. (2018) Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis. Kidney Int 93:204-213
Mansour, Sherry G; Hall, Isaac E; Reese, Peter P et al. (2018) Reliability of deceased-donor procurement kidney biopsy images uploaded in United Network for Organ Sharing. Clin Transplant 32:e13441
Manfredo Vieira, S; Hiltensperger, M; Kumar, V et al. (2018) Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science 359:1156-1161
Greiling, Teri M; Dehner, Carina; Chen, Xinguo et al. (2018) Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus. Sci Transl Med 10:
Nikonova, Anna S; Deneka, Alexander Y; Kiseleva, Anna A et al. (2018) Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD). FASEB J 32:2735-2746
van der Ven, Amelie T; Kobbe, Birgit; Kohl, Stefan et al. (2018) A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux. PLoS One 13:e0191224
Hao, Shoujin; Hao, Mary; Ferreri, Nicholas R (2018) Renal-Specific Silencing of TNF (Tumor Necrosis Factor) Unmasks Salt-Dependent Increases in Blood Pressure via an NKCC2A (Na+-K+-2Cl- Cotransporter Isoform A)-Dependent Mechanism. Hypertension 71:1117-1125

Showing the most recent 10 out of 235 publications