ENRICHMENT PROGRAM The overall objective of the Enrichment Program is to enhance the C-SiG environment by promoting education and fostering research synergy through communication amongst its members. To do this, we pursue five complementary SPECIFIC AIMS to: i) Support an infrastructure of electronic communication including internal and external C-SiG Web sites and a weekly email newsletter of C-SiG announcements and relevant seminars; ii) Conduct a monthly Center-wide seminar series, weekly seminars focused on our mechanistic themes (i.e. intracellular signaling, cell-to-cell communication, genetics and epigenetics), and regular journal clubs; iii) Organize an annual scientific minisymposium and an annual workshop topical to the center mechanistic themes; iv) Facilitate extramural collaboration and technology transfer by leveraging expertise at other institutions, including other NIDDK-funded DDRCCs via a Minisabbatical Program; and v) Nurture junior investigators by supporting an annual research career development retreat and the development of an Early Career Development and Research Training Program. In addition, the Enrichment Program will continue to plan and organize one annual conference every six years for the Midwest DDRCC Alliance (Mayo, Case Western University, University of Chicago, University of Michigan, University of Cincinnati, and Washington University).

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK084567-11
Application #
9709922
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2019-09-01
Budget End
2020-08-31
Support Year
11
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Fukushima, Masanori; Dasgupta, Debanjali; Mauer, Amy S et al. (2018) StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis. J Biol Chem 293:15277-15289
Dou, Changwei; Liu, Zhikui; Tu, Kangsheng et al. (2018) P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. Gastroenterology 154:2209-2221.e14
Kabashima, Ayano; Hirsova, Petra; Bronk, Steven F et al. (2018) Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma. J Hepatol 68:1228-1238
Masyuk, Anatoliy I; Masyuk, Tatyana V; Lorenzo Pisarello, Maria J et al. (2018) Cholangiocyte autophagy contributes to hepatic cystogenesis in polycystic liver disease and represents a potential therapeutic target. Hepatology 67:1088-1108
Knutson, Katilyn; Strege, Peter R; Li, Joyce et al. (2018) Whole Cell Electrophysiology of Primary Cultured Murine Enterochromaffin Cells. J Vis Exp :
Kanamori, Karina S; de Oliveira, Guilherme C; Auxiliadora-Martins, Maria et al. (2018) Two Different Methods of Quantification of Oxidized Nicotinamide Adenine Dinucleotide (NAD+) and Reduced Nicotinamide Adenine Dinucleotide (NADH) Intracellular Levels: Enzymatic Coupled Cycling Assay and Ultra-performance Liquid Chromatography (UPLC)-Mass Bio Protoc 8:
Orozco, Carlos A; Martinez-Bosch, Neus; Guerrero, Pedro E et al. (2018) Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk. Proc Natl Acad Sci U S A 115:E3769-E3778
Cipriani, Gianluca; Gibbons, Simon J; Miller, Katie E et al. (2018) Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice. Gastroenterology 154:2122-2136.e12
Razidlo, Gina L; Burton, Kevin M; McNiven, Mark A (2018) Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem 293:11143-11153
Kostallari, Enis; Hirsova, Petra; Prasnicka, Alena et al. (2018) Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2. Hepatology 68:333-348

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