ENRICHMENT PROGRAM The overall objective of the Enrichment Program is to enhance the C-SiG environment by promoting education and fostering research synergy through communication amongst its members. To do this, we pursue five complementary SPECIFIC AIMS to: i) Support an infrastructure of electronic communication including internal and external C-SiG Web sites and a weekly email newsletter of C-SiG announcements and relevant seminars; ii) Conduct a monthly Center-wide seminar series, weekly seminars focused on our mechanistic themes (i.e. intracellular signaling, cell-to-cell communication, genetics and epigenetics), and regular journal clubs; iii) Organize an annual scientific minisymposium and an annual workshop topical to the center mechanistic themes; iv) Facilitate extramural collaboration and technology transfer by leveraging expertise at other institutions, including other NIDDK-funded DDRCCs via a Minisabbatical Program; and v) Nurture junior investigators by supporting an annual research career development retreat and the development of an Early Career Development and Research Training Program. In addition, the Enrichment Program will continue to plan and organize one annual conference every six years for the Midwest DDRCC Alliance (Mayo, Case Western University, University of Chicago, University of Michigan, University of Cincinnati, and Washington University).

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK084567-12
Application #
9969411
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
12
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Sugihara, Takaaki; Werneburg, Nathan W; Hernandez, Matthew C et al. (2018) YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity. Mol Cancer Res 16:1556-1567
Anderson, Bradley W; Suh, Yun-Suhk; Choi, Boram et al. (2018) Detection of Gastric Cancer with Novel Methylated DNA Markers: Discovery, Tissue Validation, and Pilot Testing in Plasma. Clin Cancer Res 24:5724-5734
Rizvi, Sumera; Fischbach, Samantha R; Bronk, Steven F et al. (2018) YAP-associated chromosomal instability and cholangiocarcinoma in mice. Oncotarget 9:5892-5905
Mouchli, Mohamad A; Ouk, Lidia; Scheitel, Marianne R et al. (2018) Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer. World J Gastroenterol 24:905-916
Rizvi, Sumera; Khan, Shahid A; Hallemeier, Christopher L et al. (2018) Cholangiocarcinoma - evolving concepts and therapeutic strategies. Nat Rev Clin Oncol 15:95-111
Hale, Vanessa L; Jeraldo, Patricio; Chen, Jun et al. (2018) Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers. Genome Med 10:78
Allen, Alina M; Therneau, Terry M; Larson, Joseph J et al. (2018) Nonalcoholic fatty liver disease incidence and impact on metabolic burden and death: A 20 year-community study. Hepatology 67:1726-1736
Rizvi, Sumera; Eaton, John; Yang, Ju Dong et al. (2018) Emerging Technologies for the Diagnosis of Perihilar Cholangiocarcinoma. Semin Liver Dis 38:160-169
Strege, Peter R; Mazzone, Amelia; Bernard, Cheryl E et al. (2018) Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased NaV1.5 current and mechanosensitivity. Am J Physiol Gastrointest Liver Physiol 314:G494-G503
Bianco, F; Eisenman, S T; Colmenares Aguilar, M G et al. (2018) Expression of RAD21 immunoreactivity in myenteric neurons of the human and mouse small intestine. Neurogastroenterol Motil 30:e13429

Showing the most recent 10 out of 537 publications