The Pilot and Feasibility (P and F) Program of the Georgia Diabetes Translation Research Center (GDTRC) will serve a pivotal role in catalyzing high-return investments by helping develop junior investigators, attracting transitioning investigators, and significantly growing the breadth and depth of NIH-funded collaborative interdisciplinary diabetes translation research in the Southeast region. Of note, the P and F Program will embrace and support high impact studies in diverse populations with disproportionately high diabetes burdens. The P and F Program is a center-wide activity designed to support investigators in conducting studies that address the priority focal areas of GDTRC's Translation Research Cores: Design and Evaluation of patient- centered preventive and care services (Core B), Engagement and Behavior Change in high-risk communities (Core C), and Disparities due to a vast array of vulnerabilities (race/ethnic, gender, age, socioeconomic, co- morbidity, and geography)(Core D). The integration across GDTRC's Cores and the P and F Program ensures that pilot study investigators will be supported by Core Faculty ?nationally-recognized experts in their fields? in conducting innovative studies using state-of-the-art technologies, innovative design, and multi-disciplinary evaluation approaches. The P and F Program's main roles are: to serve as a funding catalyst (Aim 1), to support high-quality research through linkage to Faculty in GDTRC's Cores (Aim 2), and to help enhance productivity, visibility, and impacts of pilot grant recipients through offering dissemination skills training (Aim 3).
These aims will be accomplished through innovative aspects of the Program: direct matching resource commitments (totaling $182,000 per annum) from GDTRC institutions to co-support pilot studies (e.g., Emory's Division of Geriatrics has committed $20,000 annually to co-support translation studies focused on the needs of older adults with diabetes); a Micro Grants program used successfully by Emory's Center for AIDS Research where small resources to support data collection or conference travel have resulted in a 43:1 return on investment; a multi-disciplinary, multi-institutional review group to oversee the P and F award selection; close connections with the Enrichment Program to co- host skills development modules for aspiring investigators; processes to link P and F applicants with Core Faculty; an innovative mentee-to-mentor program that involves mentoring pilot grant awardees to transition to mentoring others; and efficiently leveraging other NIH-funded programs (e.g., the Atlanta Clinical and Translation Science Institute's Biostatistics and Community Engagement Cores can provide statistical and community engagement methods guidance, respectively, to investigators developing pilot grants). Based on GDTRC's broad research base and rich history of engagement with communities, clinical centers, and local and federal health agencies in the region, P and F investigators ? whether from GDTRC or regional affiliates? will have access to some of the most understudied vulnerable populations, underused but impactful datasets, and some of the finest mentors in diabetes translation research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK111024-05
Application #
10007861
Study Section
Special Emphasis Panel (ZDK1)
Project Start
2016-09-16
Project End
2021-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
5
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Umpierrez, Guillermo E; Cardona, Saumeth; Chachkhiani, David et al. (2018) A Randomized Controlled Study Comparing a DPP4 Inhibitor (Linagliptin) and Basal Insulin (Glargine) in Patients With Type 2 Diabetes in Long-term Care and Skilled Nursing Facilities: Linagliptin-LTC Trial. J Am Med Dir Assoc 19:399-404.e3
Cha, EunSeok; Paul, Sudeshna; Braxter, Betty J et al. (2018) Dietary Behaviors and Glucose Metabolism in Young Adults at Risk for Type 2 Diabetes. Diabetes Educ 44:158-167
Umpierrez, Guillermo E; Klonoff, David C (2018) Diabetes Technology Update: Use of Insulin Pumps and Continuous Glucose Monitoring in the Hospital. Diabetes Care 41:1579-1589
Gomez-Peralta, Fernando; Abreu, Cristina; Gomez-Rodriguez, Sara et al. (2018) Safety and Efficacy of DPP4 Inhibitor and Basal Insulin in Type 2 Diabetes: An Updated Review and Challenging Clinical Scenarios. Diabetes Ther 9:1775-1789
Vellanki, Priyathama; Umpierrez, Guillermo E (2018) Increasing Hospitalizations for DKA: A Need for Prevention Programs. Diabetes Care 41:1839-1841
Davis, Georgia; Fayfman, Maya; Reyes-Umpierrez, David et al. (2018) Stress hyperglycemia in general surgery: Why should we care? J Diabetes Complications 32:305-309
Ogilvie, Rachel P; Patel, Shivani A; Narayan, K M Venkat et al. (2018) Are the U.S. territories lagging behind in diabetes care practices? Prim Care Diabetes 12:432-437
Schultz, William M; Kelli, Heval M; Lisko, John C et al. (2018) Socioeconomic Status and Cardiovascular Outcomes: Challenges and Interventions. Circulation 137:2166-2178
Spanakis, Elias K; Levitt, David L; Siddiqui, Tariq et al. (2018) The Effect of Continuous Glucose Monitoring in Preventing Inpatient Hypoglycemia in General Wards: The Glucose Telemetry System. J Diabetes Sci Technol 12:20-25
Klonoff, David C; Umpierrez, Guillermo E; Rice, Mark J (2018) A Milestone in Point of Care Capillary Blood Glucose Monitoring of Critically Ill Hospitalized Patients. J Diabetes Sci Technol 12:1095-1100

Showing the most recent 10 out of 30 publications