This grant provides core support for a broad program in the Environmental Health Sciences. The research under way and proposed is broadly relevant to adverse health effects from Environmental factors. The general objectives of the research are to define the nature and extent of such effects with the aim of instituting appropriate preventive or contral procedures where required. Interests range from acute to chronic health effects including, in the latter, cancer and the degenerative diseases. The research encompasses laboratory studies on the biochemical mode of action of environmental toxicants, exploratory studies aimed at improving the reliability and efficiency of predictive toxicological tests, improvement of diagnostic procedures for disease possibly related to environmental factors, epidemiological investigations and field studies on the distribution of pollutants.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES000260-23
Application #
3102238
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1975-01-01
Project End
1989-12-31
Budget Start
1985-01-01
Budget End
1985-12-31
Support Year
23
Fiscal Year
1985
Total Cost
Indirect Cost
Name
New York University
Department
Type
Schools of Medicine
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
Roy, Nirmal K; Candelmo, Allison; DellaTorre, Melissa et al. (2018) Characterization of AHR2 and CYP1A expression in Atlantic sturgeon and shortnose sturgeon treated with coplanar PCBs and TCDD. Aquat Toxicol 197:19-31
Klocke, Carolyn; Allen, Joshua L; Sobolewski, Marissa et al. (2018) Exposure to fine and ultrafine particulate matter during gestation alters postnatal oligodendrocyte maturation, proliferation capacity, and myelination. Neurotoxicology 65:196-206
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Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096
Church, Jamie S; Tijerina, Pamella B; Emerson, Felicity J et al. (2018) Perinatal exposure to concentrated ambient particulates results in autism-like behavioral deficits in adult mice. Neurotoxicology 65:231-240
Jin, Honglei; Sun, Wenrui; Zhang, Yuanmei et al. (2018) MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer. Mol Ther Nucleic Acids 11:312-322
Chen, Danqi; Fang, Lei; Li, Hongjie et al. (2018) The effects of acetaldehyde exposure on histone modifications and chromatin structure in human lung bronchial epithelial cells. Environ Mol Mutagen 59:375-385

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