This grant provides essential core support for the principal staff of the New York University Institute of Environmental Medicine, who collectively comprise the staff of the Center. The Grant also provides important core support to the Center for shared equipment, central services, and exploratory studies. The continuity and stability of support provided by the Grant have been crucial to the development at New York University of a center of excellence for teaching and research in the environmental health sciences, which has been a resource for environmental health policy issues at the national, state, and local levels. The primary objective of research in the Center is to identify and elucidate environmental causes of disease, with the aim of developing methods for the ultimate prevention of environmentally related diseases. These objectives are being pursued through efforts to identify physical and chemical health hazards in the environment, their sources, pathways to human beings, biological effects, mechanisms of action, and dose-effect relationships. The studies involve the coordinated efforts of a full-time staff of more than 50 investigators trained in a variety of disciplines, including chemistry, physics, mathematics, biology, biochemistry, genetics, toxicology, pathology, ecology, epidemiology, engineering, and medicine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES000260-32
Application #
2152954
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1975-01-01
Project End
1995-03-31
Budget Start
1994-04-01
Budget End
1995-03-31
Support Year
32
Fiscal Year
1994
Total Cost
Indirect Cost
Name
New York University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096
Church, Jamie S; Tijerina, Pamella B; Emerson, Felicity J et al. (2018) Perinatal exposure to concentrated ambient particulates results in autism-like behavioral deficits in adult mice. Neurotoxicology 65:231-240
Jin, Honglei; Sun, Wenrui; Zhang, Yuanmei et al. (2018) MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer. Mol Ther Nucleic Acids 11:312-322
Chen, Danqi; Fang, Lei; Li, Hongjie et al. (2018) The effects of acetaldehyde exposure on histone modifications and chromatin structure in human lung bronchial epithelial cells. Environ Mol Mutagen 59:375-385
Hua, Xiaohui; Xu, Jiheng; Deng, Xu et al. (2018) New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer. Cancer Lett 436:38-51
Choi, Byeong Hyeok; Philips, Mark R; Chen, Yuan et al. (2018) K-Ras Lys-42 is crucial for its signaling, cell migration, and invasion. J Biol Chem 293:17574-17581
Peng, Minggang; Wang, Jingjing; Zhang, Dongyun et al. (2018) PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein. Oncogene :
Jose, Cynthia C; Jagannathan, Lakshmanan; Tanwar, Vinay S et al. (2018) Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. Mol Carcinog 57:794-806
Choi, Byeong Hyeok; Chen, Changyan; Philips, Mark et al. (2018) RAS GTPases are modified by SUMOylation. Oncotarget 9:4440-4450
Li, Xin; Tian, Zhongxian; Jin, Honglei et al. (2018) Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63? Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity. Mol Cell Biol 38:

Showing the most recent 10 out of 407 publications