Abstract

The Administrative CoreThe Center Director, Prof. Leona Samson, is appointed by the MIT Vice President for Research andshe is in charge of Administrative Core with assistance from the Deputy Director, Prof. Peter Dedon, and fromthe Business Manager, Ms. Gertraud Gillen. (The appointment of Prof. Peter Dedon as Deputy Director wasapproved enthusiastically by the NIEHS.) Ms. Gillen is assisted by a fiscal officer (Ms. Kathleen Reposa) anda staff assistant (Ms. Davicia Smith). Technical assistance with computer systems and informationtechnology for the Center is provided by the Center IT Specialist, Ms. Patricia Brown. The EnvironmentalHealth and Safety Officer, Mr. Joseph Glogowski, is responsible for monitoring safety issues related toradiation, chemical and biological hazards in the Center in accord with MIT Environmental Health and Safetyguidelines.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES002109-29
Application #
7700318
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2008-04-01
Project End
2010-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
29
Fiscal Year
2008
Total Cost
$268,569
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Wang, Xin; Garcia, Carlos T; Gong, Guanyu et al. (2018) Automated Online Solid-Phase Derivatization for Sensitive Quantification of Endogenous S-Nitrosoglutathione and Rapid Capture of Other Low-Molecular-Mass S-Nitrosothiols. Anal Chem 90:1967-1975
Moore, Christopher L; Papa 3rd, Louis J; Shoulders, Matthew D (2018) A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo. J Am Chem Soc 140:11560-11564
Chan, Cheryl; Pham, Phuong; Dedon, Peter C et al. (2018) Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses. Genome Biol 19:228
Tam, Brooke E; Hao, Yining; Sikes, Hadley D (2018) An examination of critical parameters in hybridization-based epigenotyping using magnetic microparticles. Biotechnol Prog 34:1589-1595
Li, Weiwei; Chan, Chi-Kong; Liu, Yushuo et al. (2018) Aristolochic Acids as Persistent Soil Pollutants: Determination of Risk for Human Exposure and Nephropathy from Plant Uptake. J Agric Food Chem 66:11468-11476
Ge, Zhongming; Sheh, Alexander; Feng, Yan et al. (2018) Helicobacter pylori-infected C57BL/6 mice with different gastrointestinal microbiota have contrasting gastric pathology, microbial and host immune responses. Sci Rep 8:8014
Yuan, Yifeng; Hutinet, Geoffrey; Valera, Jacqueline Gamboa et al. (2018) Identification of the minimal bacterial 2'-deoxy-7-amido-7-deazaguanine synthesis machinery. Mol Microbiol 110:469-483
Mannion, Anthony; Shen, Zeli; Fox, James G (2018) Comparative genomics analysis to differentiate metabolic and virulence gene potential in gastric versus enterohepatic Helicobacter species. BMC Genomics 19:830
Kulik, Heather J (2018) Large-scale QM/MM free energy simulations of enzyme catalysis reveal the influence of charge transfer. Phys Chem Chem Phys 20:20650-20660
Rizzo, Alessandro A; Vassel, Faye-Marie; Chatterjee, Nimrat et al. (2018) Rev7 dimerization is important for assembly and function of the Rev1/Pol? translesion synthesis complex. Proc Natl Acad Sci U S A 115:E8191-E8200

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