Abstract

The Pilot Project Program has always played a major role in defining the identity ofthe MIT CEHS and in refreshing the Center membership. In addition to open calls for proposals to the MIT community, the Program complements the Director's Opportunity Fund by providing a means to target the development of new research areas in environmental health sciences and toxicology and to foster new activities such as the Global EHS Program, with focused calls for proposals. The funds used to support the Pilot Project Program, which amounted to $638K in the past funding period, represent a sound investment in EHS research at MIT, with a 17-fold return in terms of leveraging new grant funding. The Pilot Project Program will continue to be of central importance to the CEHS in the next funding period.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES002109-34
Application #
8650833
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
34
Fiscal Year
2014
Total Cost
$206,881
Indirect Cost
$72,740

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Rothenberg, Daniel A; Taliaferro, J Matthew; Huber, Sabrina M et al. (2018) A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. iScience 9:367-381
Brody, Yehuda; Kimmerling, Robert J; Maruvka, Yosef E et al. (2018) Quantification of somatic mutation flow across individual cell division events by lineage sequencing. Genome Res 28:1901-1918
Freedman, Adam J E; Peet, Kyle C; Boock, Jason T et al. (2018) Isolation, Development, and Genomic Analysis of Bacillus megaterium SR7 for Growth and Metabolite Production Under Supercritical Carbon Dioxide. Front Microbiol 9:2152
Dudani, Jaideep S; Ibrahim, Maria; Kirkpatrick, Jesse et al. (2018) Classification of prostate cancer using a protease activity nanosensor library. Proc Natl Acad Sci U S A 115:8954-8959
Nakashige, Toshiki G; Bowman, Sarah E J; Zygiel, Emily M et al. (2018) Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site. Biochemistry 57:4155-4164
Ganesh, B P; Hall, A; Ayyaswamy, S et al. (2018) Diacylglycerol kinase synthesized by commensal Lactobacillus reuteri diminishes protein kinase C phosphorylation and histamine-mediated signaling in the mammalian intestinal epithelium. Mucosal Immunol 11:380-393
Bauwens, Eva; Joosten, Myrthe; Taganna, Joemar et al. (2018) In silico proteomic and phylogenetic analysis of the outer membrane protein repertoire of gastric Helicobacter species. Sci Rep 8:15453
Lo, Justin H; Hao, Liangliang; Muzumdar, Mandar D et al. (2018) iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer. Mol Cancer Ther 17:2377-2388
Richardson, Christopher E R; Cunden, Lisa S; Butty, Vincent L et al. (2018) A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. J Am Chem Soc 140:2413-2416
Hagen, Susan J; Ang, Lay-Hong; Zheng, Yi et al. (2018) Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach. Gastroenterology 155:1852-1867

Showing the most recent 10 out of 970 publications