A. Objectives, Rationale and Specific AimsThe primary purpose of the Exposure Assessment Facility Core is to enhance the research capabilities ofCenter for Environmental Health in Northern Manhattan (CEHNM) investigators by providing expertise in anumber of related activities and services not available elsewhere in the University, including exposure design,method development, sampling and analysis.This Facility Core supports the development and implementation of exposure assessments in support offunded research, pilot studies, new research initiatives, and outreach activities of the CEHNM by coordinatingthe following services and activities: study design, methods development, design and development of new sampling equipment, airsampling, and analytical capabilities; expansion of these facilities and efforts in ways that support the evolving strategic goals of the CEHNM;. training and mentoring of staff, students and researchers; responding to exposure emergencies; responding to the needs of the Community Outreach and Education Core (COEC) and local communityograniziations in a number of ways, including testifying in public hearings and carrying out pilot fieldwork to test whether perceived sources of air pollution exist and can be documented.This Facility Core combines analytical capabilities and expertise at the Mailman School of Public Health(MSPH) and Lamont-Doherty Earth Observatory (LDEO). The primary focus of the Exposure AssessmentFacility Core is on sampling and analysis of environmental rather than biological samples. The analysis ofbiomarkers of exposure are addressed by the Trace Metals Facility Core and the Integrative Health SciencesFacility Core, with the exception of lead isotope ratios in blood, which are analyzed at LDEO. A major strengthof the CEHNM is the multiple working groups that are developing new initiatives and projects. Members of theExposure Core participate in many of these groups to assist in the design of new exposure methods andmarkers that address specific research goals.
The Specific Aims of the Exposure Assessment Facility Core are as follows:
Specific Aim 1 : To provide an infrastructure to assist CEHNM members and Pilot Project awardees carry outhuman studies of environmental exposures. The core will provide assistance in: a) Exposure assessment studydesigns; b) Design and development of new samplers; c) Development of analytical methods; d) Analysis ofenvironmental samples for mass, black carbon, trace elements, isotope ratios, allergens, molds, gasconcentrations, and trace organics); and e) Lending of monitoring equipment.
Specific Aim 2 : To provide mentoring and training to CEHNM members, students and postdoctoral fellows,and community partners.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES003819-21
Application #
7434799
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2008-04-01
Project End
2013-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
21
Fiscal Year
2008
Total Cost
$171,459
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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