Abstract

The goal of this renewal application for the NIEHS Center at EOHSI in Piscataway, NJ is to provide support and continuity to our mission of improving environmental and public health through research, education, outreach and communication. The EHS center serves New Jersey, the most densely populated and perhaps the most heavily polluted state in the nation. The grant proposal consists of 4 Research Cores, 8 Facility Cores, a COEP and a Pilot Project Program. The Cores are as follows: I. Biotransformation and Toxicity of Environmental Chemicals II. Environmental Effects on Signal Transduction III. Neural and Developmental Toxicology IV. Exposure Analysis and Health Effects Community Outreach and Education Program (COEP) Facility Cores are: Analytical Cytometry and Image Analysis Chemical Analysis Clinical Studies Laboratory (developing) Enzymes and antibodies Exposure/Dosimetry Modeling Molecular Genetics Molecular Pathology Statistical Analyses

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES005022-12
Application #
2900393
Study Section
Special Emphasis Panel (ZES1-EBJ-C (01))
Project Start
1988-09-28
Project End
2003-03-31
Budget Start
1999-04-01
Budget End
2000-03-31
Support Year
12
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Fournier, S B; D'Errico, J N; Stapleton, P A (2018) Engineered nanomaterial applications in perinatal therapeutics. Pharmacol Res 130:36-43
Stapleton, P A; Hathaway, Q A; Nichols, C E et al. (2018) Maternal engineered nanomaterial inhalation during gestation alters the fetal transcriptome. Part Fibre Toxicol 15:3
Fiedler, Nancy; Weisel, Clifford; Nwankwo, Chizoba et al. (2018) Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med 60:e663-e670
Therkorn, Jennifer; Calderon, Leonardo; Cartledge, Benton et al. (2018) Inactivation of Pure Bacterial Biofilms by Impaction of Aerosolized Consumer Products Containing Nanoparticulate Metals. Environ Sci Nano 5:544-555
Lee, Heedoo; Zhang, Duo; Laskin, Debra L et al. (2018) Functional Evidence of Pulmonary Extracellular Vesicles in Infectious and Noninfectious Lung Inflammation. J Immunol 201:1500-1509
Del Giudice, Marco; Barrett, Emily S; Belsky, Jay et al. (2018) Individual differences in developmental plasticity: A role for early androgens? Psychoneuroendocrinology 90:165-173
Barrett, E S; Hoeger, K M; Sathyanarayana, S et al. (2018) Anogenital distance in newborn daughters of women with polycystic ovary syndrome indicates fetal testosterone exposure. J Dev Orig Health Dis 9:307-314
George, Blessy; Joy, Melanie S; Aleksunes, Lauren M (2018) Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy. Exp Biol Med (Maywood) 243:272-282
Vail, Gwyndolin; Roepke, Troy A (2018) Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system. Steroids :
Tiethof, Angela K; Richardson, Jason R; Hart, Ronald P (2018) Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells. Toxics 6:

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