Abstract

The Biological Response Indicators Facility Core (BRIG) uses basic and applied research tools and methodology to help investigators identify markers of susceptibility and exposure that may be linked to disease pathogenesis. The Core uses a single administrative structure to provide services in three specific areas: DNA/RNA Analysis (A. Brooks), Flow Cytometry/lmage Analysis (D. Laskin) and Molecular Pathology (K. Reuhl and E. Richfield). The Core works closely with the Integrative Health Sciences Facility Core (IHSFC) and the Bioinformatics, Biostatistics and Computational Toxicology Facility Core on issues of experimental design. The Core provides standard operating procedures and technology training to Center investigators. The BRI Core also coordinates with studies initiated through the IHSFC and other Facility Core, and initiates sample tracking through the Center's Laboratory Information Management System (LIMS).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005022-21
Application #
7790082
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
21
Fiscal Year
2009
Total Cost
$357,083
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Type
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Tiethof, Angela K; Richardson, Jason R; Hart, Ronald P (2018) Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells. Toxics 6:
Liu, Anna B; Tao, Siyao; Lee, Mao-Jung et al. (2018) Effects of gut microbiota and time of treatment on tissue levels of green tea polyphenols in mice. Biofactors :
Rockafellow-Baldoni, Megan; Spayd, Steven E; Hong, Jun-Yan et al. (2018) Arsenic Exposure and Cancer Risk Reduction with Local Ordinance Requiring Whole-House Dual-Tank Water Treatment Systems. Hum Ecol Risk Assess 24:1256-1267
Jabbar, Shaima; Reuhl, Kenneth; Sarkar, Dipak K (2018) Prenatal alcohol exposure increases the susceptibility to develop aggressive prolactinomas in the pituitary gland. Sci Rep 8:7720
Radbel, Jared; Le-Hoang, Oanh; Vayas, Kinal N et al. (2018) Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice. Ann Am Thorac Soc 15:S125-S126
Walley, Sabrina N; Roepke, Troy A (2018) Perinatal exposure to endocrine disrupting compounds and the control of feeding behavior-An overview. Horm Behav 101:22-28
Szilagyi, John T; Fussell, Karma C; Wang, Yun et al. (2018) Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase. Toxicol Appl Pharmacol 359:102-107
Li, Wenji; Yang, Hilly; Buckley, Brian et al. (2018) A Novel Triple Stage Ion Trap MS method validated for curcumin pharmacokinetics application: A comparison summary of the latest validated curcumin LC/MS methods. J Pharm Biomed Anal 156:116-124
Cory-Slechta, D A; Allen, J L; Conrad, K et al. (2018) Developmental exposure to low level ambient ultrafine particle air pollution and cognitive dysfunction. Neurotoxicology 69:217-231
Joseph, Laurie B; Composto, Gabriella M; Perez, Roberto M et al. (2018) Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol Lett 293:77-81

Showing the most recent 10 out of 819 publications